Scientist, Discovery

Role Summary

As a Scientist, your mission is to execute protein and molecular biology engineering strategies to advance projects within Arcellx’s Discovery group. Engaging with a cross-functional team in a fast-paced environment, you’ll identify and develop Arcellx’s lead therapeutic candidates. Our potentially life-saving treatments would not exist without the work of our talented Discovery scientists; this role will have a tremendous impact on our pipeline and ability to deliver novel and effective drugs to patients.

Responsibilities

• Work with an interdisciplinary team of scientists to design, engineer and express recombinant proteins for use in the discovery and development of cancer therapies.
• Design, construct and evaluate expression plasmids. Perform transfections, transductions, phage and yeast display enabled selections & screenings, binding kinetic assessments and flow cytometry as needed.
• Develop new methods, technologies and processes when necessary for project.
• Exercise significant technical discretion in the design, execution and interpretation of experiments.
• Communicate progress and project recommendations to team members.

Qualifications

• Required: BS or MS in the life sciences (e.g., biology, genetics, biochemistry, chemistry, chemical engineering, bioengineering) with 4-8 years post-degree lab experience or PhD in the life sciences with 0-3 years post-degree experience.
• Required: Must demonstrate mastery of molecular biology methods, including primer design, PCR, gel electrophoresis, expression construct design cloning and sequence analysis.
• Preferred: methods for the characterization of recombinant protein quality and binding, protein display (phage, yeast and library preparation).
• Preferred: experience in drug development, immunology or protein engineering.
• Required: The ability to independently plan, organize, and prioritize work activities. The ability to work collaboratively in interdisciplinary teams.

Skills

• Mastery of molecular biology methods, including primer design, PCR, gel electrophoresis, expression construct design cloning and sequence analysis.
• Experience with protein engineering and display technologies is advantageous.
• Strong collaboration and communication skills in cross-functional teams.

Education

• BS or MS in the life sciences with 4-8 years post-degree lab experience or PhD in the life sciences with 0-3 years post-degree experience.

Additional Requirements

• None specified beyond the qualifications and responsibilities above.