Scientist - CV Renal, Histology and In vivo

Role Summary

Scientist - CV Renal, Histology and In vivo. A dynamic and collaborative scientist contributing to cutting-edge research at the intersection of in vivo, histology, and in vitro studies. Designs and executes preclinical studies, develops histological techniques, and supports in vitro assay development within a cross-functional team.

Responsibilities

• Collaborate with cross-functional teams to design, manage, and execute studies utilizing mouse models.
• Administer compounds through various methods, including intraperitoneal, subcutaneous, and intravenous dosing.
• Collect, process, and document biological samples (e.g., blood, tissues, organs) for downstream histological and molecular analyses, ensuring alignment with project goals across teams.
• Optimize and validate histological endpoints to support preclinical research projects.
• Perform histological techniques such as IHC, ICC, RNAscope, and related methods, ensuring rigor and reproducibility.
• Coordinate sample management to handle, fix, embed, section, and prepare tissues for high-quality histological analysis.
• Collaborate with data scientists to utilize imaging and quantitative analysis software, interpret histological data, and generate insights.
• Prepare detailed reports and present findings to internal teams, bridging research and development functions.
• Drive improvements in histological workflows and protocols in collaboration with cross-functional teams.
• Collaborate with other functional groups to culture mammalian cells and assist in the development of cell-based assays.
• Apply immunocytochemistry and immunoblotting to support mechanistic studies and integrate findings into broader research initiatives.

Qualifications

• Required: BS or MS with 6+ years of experience in histology and in vivo techniques.
• Preferred: Kidney-specific histological techniques are a plus; experience in preclinical research.

Skills

• Histology techniques (IHC, ICC, RNAscope, etc.)
• In vivo pharmacology and animal model work
• Cell culture and cell-based assay development
• Data analysis and imaging software
• Strong documentation and communication of results

Education

• BS or MS in a related field; additional advanced degrees beneficial