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Scientist, Computational Chemist & MLOps Engineer

Arrowhead Pharmaceuticals
August 28, 2026
Full-time
Remote friendly (Madison, WI)
Worldwide
Clinical Research and Development
Role: Computational Scientist supporting machine learning-driven drug discovery at Arrowhead Pharmaceuticals, focusing on data engineering, statistical modeling, and bioinformatics for therapeutic design programs. Responsibilities: develop and apply models to biological datasets, design and maintain data pipelines, build reproducible workflows, analyze high-dimensional data, contribute software in Python, operate in Linux/HPC/cloud environments, ensure reproducibility, and collaborate with multidisciplinary teams. Requirements: Bachelorโ€™s/Masterโ€™s in Bioinformatics, Computational Biology, or related; strong Python skills; Linux command-line experience; foundational knowledge of statistics and machine learning; experience with biological datasets and version control (Git). Senior level (Scientist III) prefers PhD, independent project leadership, and mentoring experience. Preferred: expertise in predictive modeling, deep learning, RNA biology, genomics, bioinformatics workflows, and large-scale omics data. The role offers a salary range of $100,000-$125,000 USD, based in WI or CA, with a focus on biopharma research involving genetic-based medicines, RNAi therapeutics, and innovative platform development. No specific travel or work setup details provided.