Scientist - Cellular Immunology Preclinical
Cabaletta Bio
August 27, 2026
Full-time
On-site
Philadelphia, PA
Clinical Research and Development
Role: Scientist specializing in cell-based assays for CAR T cell therapy within the Cellular Immunology Preclinical Department. Objectives include developing in vitro, ex vivo, and in vivo assays to improve the safety and efficacy profiles of CAR T therapies targeting autoimmune diseases. Responsibilities encompass conducting cell culture, cytotoxicity, flow cytometry, ELISpot, ELISA, and other immunological assays; overseeing mouse studies; maintaining lab equipment; analyzing data; and collaborating with multidisciplinary teams. Requirements: Ph.D. in Immunology, Cell Biology, or related field with 0-2 years, or Master's with at least 5 years, or Bachelor's with a minimum of 10 years of relevant experience. Must have hands-on experience with mammalian cell culture, primary immune cell handling, cytotoxicity tests, flow cytometry, and animal studies. Skills in lab organization, protocol adherence, data analysis, and communication are essential. Preferred qualifications include extensive primary immune cell culture expertise and industry or startup experience. High-value details include focus on CAR T cell therapies for autoimmune indications, preclinical research, and work in a biotech setting. Location: On-site in Philadelphia, PA.