Scientist, Bioscience Immunology

Role: Immunology scientist focused on elucidating immune pathways related to autoimmune diseases within AstraZeneca's Cambridge labs. Primary objectives include characterizing immune mechanisms, driving target validation, and informing drug discovery strategies. Responsibilities encompass designing and executing in vitro and ex vivo studies using primary and disease tissue-derived human cells, developing and validating cellular and molecular assays, analyzing complex datasets with rigorous statistical approaches, and collaborating cross-functionally to align research efforts and incorporate external innovations. The role involves leading aspects of biological research, contributing to program strategy, and publishing findings in reputable journals. Requirements: Master's degree in immunology or related field with 3+ years of relevant experience or Ph.D. with postdoctoral experience; expertise in immunology, drug discovery, and advanced cell-based assays such as flow cytometry, ELISA, Western blot, and multiplex cytokine read-outs. Strong communication and organizational skills are essential. Preferred: biotech/pharma experience. High-value details include focus on immune-mediated diseases, predominantly working with human in vitro systems, and the emphasis on assay development, data integrity, and scientific leadership within AstraZeneca’s innovative research environment. Location: Cambridge, MA; work is lab-based. The position offers competitive salary, benefits, and opportunities for scientific impact.