Scientist, Biology
Gilead Sciences
6 hours ago
On-site
San Francisco Bay Area
Clinical Research and Development
Key Responsibilities:
- Lead development and establishment of high-throughput bioanalytical methods to support preclinical PK studies of large molecules and ADCs.
- Independently design, develop, optimize and run bioanalytical assays using ligand binding and mass analytical techniques, leveraging robotic automation.
- Independently analyze, interpret, and report bioanalytical and pharmacokinetic data with scientific rigor using industry standard analytical tools.
- Operate and maintain analytical instruments such as LC-MS systems and ligand binding assay platforms.
- Prepare and deliver internal scientific reports, presentations, and documentation.
- Independently identify opportunities to improve current approaches and propose innovative solutions to expand the capabilities of the bioanalytical function.
Basic Qualifications:
- 6+ years with BS
- OR 4+ years with MS
- OR 0+ years with PhD/PharmD
Preferred Qualifications:
- BS with 6+ years; MS with 4+ years; PhD with 0+ years in Pharmaceutical Sciences, Chemistry, Biochemistry, Biology, or related discipline.
- 2–5 years of hands-on industry experience in bioanalysis and PK.
- Expert knowledge of ligand binding bioanalysis methods; hands-on immunoprecipitation, enzymatic digestion, LC-MS/MS, MSD platforms, and ligand binding assays.
- Ability to perform specimen processing, extraction, and quantification of biologics, small molecules, ADCs, and small-molecule payloads, including biotransformation analysis.
- Proficiency with non-compartmental PK analysis software such as Phoenix NonWinLin.
- Strong organizational skills, attention to detail, and effective time management.
- Experience standardizing and implementing bioanalytical methods.
- Proficiency with lab automation.
- Experience with in vitro screening assay technologies.
- Familiarity with HTS (96/384/1536-well formats) and laboratory automation.
Core Competencies:
- Thrive in fast-paced environment.
- Strong ownership and accountability.
- Critical thinking and problem solving.
- Detail-oriented with big-picture thinking.
- Strong work ethic.
- Effective multitasking.
- Excellent communication skills.
- Collaborative and open-minded.
Benefits (if applicable per role):
- May be eligible for discretionary annual bonus, discretionary stock-based long-term incentives, paid time off, and a benefits package (company-sponsored medical, dental, vision, and life insurance).
Application Instructions:
- For current Gilead employees and contractors: apply via the Internal Career Opportunities portal in Workday.
- Lead development and establishment of high-throughput bioanalytical methods to support preclinical PK studies of large molecules and ADCs.
- Independently design, develop, optimize and run bioanalytical assays using ligand binding and mass analytical techniques, leveraging robotic automation.
- Independently analyze, interpret, and report bioanalytical and pharmacokinetic data with scientific rigor using industry standard analytical tools.
- Operate and maintain analytical instruments such as LC-MS systems and ligand binding assay platforms.
- Prepare and deliver internal scientific reports, presentations, and documentation.
- Independently identify opportunities to improve current approaches and propose innovative solutions to expand the capabilities of the bioanalytical function.
Basic Qualifications:
- 6+ years with BS
- OR 4+ years with MS
- OR 0+ years with PhD/PharmD
Preferred Qualifications:
- BS with 6+ years; MS with 4+ years; PhD with 0+ years in Pharmaceutical Sciences, Chemistry, Biochemistry, Biology, or related discipline.
- 2–5 years of hands-on industry experience in bioanalysis and PK.
- Expert knowledge of ligand binding bioanalysis methods; hands-on immunoprecipitation, enzymatic digestion, LC-MS/MS, MSD platforms, and ligand binding assays.
- Ability to perform specimen processing, extraction, and quantification of biologics, small molecules, ADCs, and small-molecule payloads, including biotransformation analysis.
- Proficiency with non-compartmental PK analysis software such as Phoenix NonWinLin.
- Strong organizational skills, attention to detail, and effective time management.
- Experience standardizing and implementing bioanalytical methods.
- Proficiency with lab automation.
- Experience with in vitro screening assay technologies.
- Familiarity with HTS (96/384/1536-well formats) and laboratory automation.
Core Competencies:
- Thrive in fast-paced environment.
- Strong ownership and accountability.
- Critical thinking and problem solving.
- Detail-oriented with big-picture thinking.
- Strong work ethic.
- Effective multitasking.
- Excellent communication skills.
- Collaborative and open-minded.
Benefits (if applicable per role):
- May be eligible for discretionary annual bonus, discretionary stock-based long-term incentives, paid time off, and a benefits package (company-sponsored medical, dental, vision, and life insurance).
Application Instructions:
- For current Gilead employees and contractors: apply via the Internal Career Opportunities portal in Workday.