Scientist, Biologics Production

Role Summary

Scientist in Biologics Production responsible for supporting high-throughput, automation-first biologics production, spanning mammalian expression, purification, and analytics. Focus on compressing DNA-to-material timelines for discovery programs and technology development, delivering molecules and data packages.

Responsibilities

• Aid and execute in improving the sequence-to-material pipeline: transient CHO/HEK expression, purification, and QC assessment of IgGs, VHH (+/- Fc), and multispecifics using high-throughput workflows.
• Predictive analytical QC routes to inform purification groups and meet therapy area demand for decision-quality materials and technology development initiatives.
• Automated liquid-handling workflows related to biologics purification (monospecific and multispecific) and analytical stations (SEC-HPLC or UPLC, CE-SDS).
• Embed data integrity and compliance across workflows via Genedata Biologics, eLN, and Smartsheet governance and training.
• Maintain in-process controls and release-for-use criteria in partnership with Analytics and Developability, including SEC, CE-SDS, Endotoxin, and HCP.
• Partner with Protein Engineering and Novel Modalities, Assays/Profiling and Pharmacology, and PS&A Analytics and Developability; collaborate with Purification Process Sciences for scale-up readiness.

Qualifications

• Required: B.S. in Biochemistry, Biochemical Engineering, or closely related field.
• Required: 2‚Äì4+ years in biologics production and purification in biotech or pharma; experience in mammalian expression and purification/QC (transient CHO or HEK-derived).
• Required: Digital and compliance acumen with Genedata Biologics and eLN or Smartsheet-based governance.

Desirable Skills/Experience

• Hands-on experience with Hamilton liquid-handling platforms for protein purification and normalization.
• Coordination and planning of liquid handler usage and routine operation.
• Experience with Unchained Labs instruments for UV/Vis and data management transfer into liquid handling platforms.
• Programming knowledge is a plus.