Scientist
GSK
Full-time
On-site
Collegeville, PA
Clinical Research and Development
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Role Summary
Scientist to join the iPSC Systems team within the Human Biology - Target Discovery department at GSK's Upper Providence research facility. This lab-based role focuses on advancing iPSC-derived translational models for neurodegenerative diseases, with emphasis on Alzheimer's Disease. Requires expertise in iPSC culture/differentiation, molecular biology, data analysis, automated liquid handling, and data analysis experience.
Responsibilities
- Develop physiological and disease-relevant cellular models and refine assays to achieve research objectives.
- Communicate experimental findings effectively, both in writing and verbally, to stakeholders.
- Ensure compliance with all GSK R&D integrity practices, ethical codes, standards, and safety protocols.
- Collaborate in a matrix team environment, contributing to high scientific standards and project success.
Qualifications
- Required: Bachelor’s or master’s degree in Biochemistry, Molecular and Cellular Biology, Neuroscience, or related field, with 5+ or 3+ years of experience in iPSC-model development.
- Required: Expertise in iPSC culture and differentiation.
- Required: Experience in genetic, proteomic, imaging, and other 'omics technologies analytical pipelines.
- Required: Experience in neurodegenerative diseases.
- Required: Experience analyzing, summarizing, and interpreting experimental data with meticulous record-keeping.
- Preferred: Experience in programming and operating automated liquid handling systems.
- Preferred: Strong relationship-building, adaptable thinking, and troubleshooting skills.
- Preferred: Experience conducting perturbation studies using tool compounds and gene editing techniques, preferably CRISPRn/i/a.
Skills
- iPSC culture and differentiation
- Data analysis and interpretation
- Molecular biology techniques
- Automated liquid handling systems
- Communication and collaboration in cross-functional teams
Education
- Bachelor’s or master’s degree in Biochemistry, Molecular and Cellular Biology, Neuroscience, or related field
Additional Requirements
- On-site, lab-based role at Upper Providence location