Scientific Director, Pathology
Takeda
August 20, 2026
On-site
Boston, MA
$177,000 - $278,080 USD yearly
Clinical Research and Development
Objective / Purpose
- Provide scientific and strategic leadership to embed AI/ML-enabled pathology and digital pathology into nonclinical research workflows.
- Partner with the NCSP iDigPath team to advance AI/ML for quantitative, high-content pathology analysis to improve sensitivity, reproducibility, and translational relevance of tissue endpoints.
- Implement workflows integrating digital pathology into target validation, efficacy/safety assessment strategies, primary evaluation and peer review of specimens/data, and study reports.
Accountabilities
- Serve as an NCSP Project Pathologist and/or Project Toxicology representative; provide anatomic/clinical pathology and toxicology expertise and collaborate with R&D leaders.
- Lead pathology contributions to target validation and MoA understanding via integrated pathology, pharmacology, and biomarker interpretation.
- Provide scientific leadership for fit-for-use qualification of AI/ML pathology tools and digital endpoints, including governance for data quality and model performance.
- Provide IHC, ISH, and spatial endpoint expertise with iPath/iTox, DMPK, and Drug Discovery Units.
- Perform and peer-review macroscopic/microscopic primary reads of animal tissues; communicate findings and recommendations via reports and meetings.
- Author/review regulatory documents (BB, IND, IB, DSUR, BLA, MAA, NDA, JNDA) and respond to health authorities.
- Represent Takeda in toxicology/pathology meetings and professional committees/consortia.
Education & Qualifications
- DVM (or equivalent) and Ph.D.
- Board certification (ACVP/ECVP/JCVP).
- Proficiency in veterinary anatomic and/or clinical pathology.
- 10+ years pharmaceutical drug development experience.
- Experience with alternative modalities (desired): oligonucleotides, antibodies/conjugates, small molecules, alternative routes.
Skills
- Strong decision-making, data analysis/interpretation, critical thinking.
- Excellent written/oral communication; leadership and collaboration/mentoring.
- Working knowledge of digital pathology platforms (Halo-link, Halo, Visopharm, Patholytix, Pristima/Provantis, Benchling ELN) and quantitative image analysis.
- Track record leading transformational initiatives in digital pathology/computational biology/translational science.
Compensation & Benefits (if applicable)
- U.S. Base Salary Range (Boston, MA): $177,000.00–$278,080.00.
- Possible incentives and benefits (medical/dental/vision, 401(k) match, disability, life insurance, tuition reimbursement, paid time off, etc.).
Application Instructions
- Apply via the “Apply” button and provide information processed under Takeda’s Privacy Notice and Terms of Use.
- Provide scientific and strategic leadership to embed AI/ML-enabled pathology and digital pathology into nonclinical research workflows.
- Partner with the NCSP iDigPath team to advance AI/ML for quantitative, high-content pathology analysis to improve sensitivity, reproducibility, and translational relevance of tissue endpoints.
- Implement workflows integrating digital pathology into target validation, efficacy/safety assessment strategies, primary evaluation and peer review of specimens/data, and study reports.
Accountabilities
- Serve as an NCSP Project Pathologist and/or Project Toxicology representative; provide anatomic/clinical pathology and toxicology expertise and collaborate with R&D leaders.
- Lead pathology contributions to target validation and MoA understanding via integrated pathology, pharmacology, and biomarker interpretation.
- Provide scientific leadership for fit-for-use qualification of AI/ML pathology tools and digital endpoints, including governance for data quality and model performance.
- Provide IHC, ISH, and spatial endpoint expertise with iPath/iTox, DMPK, and Drug Discovery Units.
- Perform and peer-review macroscopic/microscopic primary reads of animal tissues; communicate findings and recommendations via reports and meetings.
- Author/review regulatory documents (BB, IND, IB, DSUR, BLA, MAA, NDA, JNDA) and respond to health authorities.
- Represent Takeda in toxicology/pathology meetings and professional committees/consortia.
Education & Qualifications
- DVM (or equivalent) and Ph.D.
- Board certification (ACVP/ECVP/JCVP).
- Proficiency in veterinary anatomic and/or clinical pathology.
- 10+ years pharmaceutical drug development experience.
- Experience with alternative modalities (desired): oligonucleotides, antibodies/conjugates, small molecules, alternative routes.
Skills
- Strong decision-making, data analysis/interpretation, critical thinking.
- Excellent written/oral communication; leadership and collaboration/mentoring.
- Working knowledge of digital pathology platforms (Halo-link, Halo, Visopharm, Patholytix, Pristima/Provantis, Benchling ELN) and quantitative image analysis.
- Track record leading transformational initiatives in digital pathology/computational biology/translational science.
Compensation & Benefits (if applicable)
- U.S. Base Salary Range (Boston, MA): $177,000.00–$278,080.00.
- Possible incentives and benefits (medical/dental/vision, 401(k) match, disability, life insurance, tuition reimbursement, paid time off, etc.).
Application Instructions
- Apply via the “Apply” button and provide information processed under Takeda’s Privacy Notice and Terms of Use.