Scientific Director II, Translational Precision Medicine, Neuroscience
AbbVie
3 months ago
Remote friendly (Waltham, MA)
United States
Clinical Research and Development
Purpose:
- Translational scientist in Precision Medicine Neuroscience bridging basic brain/nervous system research and clinical applications to develop biological and disease insights for neurological and psychiatric disorders.
Responsibilities:
- Uncover neurobiological mechanisms of disease to elucidate patient subtypes; mechanisms of action, response, or resistance; and advance novel interventions.
- Develop testable hypotheses related to neurobiological pathways, neuronal circuitry, cognitive/behavioral domains, and/or functional markers of disease or patient subtypes to advance pipeline and disease area goals; collaborate with PMed DAS leads and other functional leads to execute actionable approaches.
- Shape and enhance human neuroscience efforts, promoting research synergies with other R&D areas aligned to disease area strategic goals.
- Drive scientific strategy for translational biomarker development and discovery target validation/MOA projects.
- Lead design of clinically translational experiments with PMED, clinical leads, or translational discovery teams.
- Establish external collaborations to augment internal efforts and expand experimental design options.
- Ensure quality and effectiveness of major precision medicine project plans via sound design and early risk assessment.
- Advance clinical translational efforts through stakeholder alignment and navigation of current/emerging business challenges.
- Communicate expertise and learnings through advising and knowledge-sharing with subordinates, peers, and senior management.
- Source and leverage emerging scientific trends from inside and outside the organization.
Qualifications:
- Bachelor’s degree in science with 24 years related experience; or Master’s degree in science with 18 years; or PhD/equivalent terminal degree (or PharmD/MD) with 14 years.
- Relevant experience in biology, target validation, and biomarker research (neural circuits; functional domains using clinical science approaches such as cognitive/emotional/behavioral; liquid-based methods; structural/functional imaging); expert in at least one.
- Knowledge of the drug development process and proven integration into clinical translation with a track record advancing multiple assets to POC or beyond.
- Proven leadership directing/leading/learning from cross-functional teams, including leading a team of translational scientists.
- Strong presentation skills to scientists and nonscientists.
Benefits (as stated):
- Comprehensive benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance, and 401(k) for eligible employees.
Additional/Application instructions:
- Not provided in the text.
- Translational scientist in Precision Medicine Neuroscience bridging basic brain/nervous system research and clinical applications to develop biological and disease insights for neurological and psychiatric disorders.
Responsibilities:
- Uncover neurobiological mechanisms of disease to elucidate patient subtypes; mechanisms of action, response, or resistance; and advance novel interventions.
- Develop testable hypotheses related to neurobiological pathways, neuronal circuitry, cognitive/behavioral domains, and/or functional markers of disease or patient subtypes to advance pipeline and disease area goals; collaborate with PMed DAS leads and other functional leads to execute actionable approaches.
- Shape and enhance human neuroscience efforts, promoting research synergies with other R&D areas aligned to disease area strategic goals.
- Drive scientific strategy for translational biomarker development and discovery target validation/MOA projects.
- Lead design of clinically translational experiments with PMED, clinical leads, or translational discovery teams.
- Establish external collaborations to augment internal efforts and expand experimental design options.
- Ensure quality and effectiveness of major precision medicine project plans via sound design and early risk assessment.
- Advance clinical translational efforts through stakeholder alignment and navigation of current/emerging business challenges.
- Communicate expertise and learnings through advising and knowledge-sharing with subordinates, peers, and senior management.
- Source and leverage emerging scientific trends from inside and outside the organization.
Qualifications:
- Bachelor’s degree in science with 24 years related experience; or Master’s degree in science with 18 years; or PhD/equivalent terminal degree (or PharmD/MD) with 14 years.
- Relevant experience in biology, target validation, and biomarker research (neural circuits; functional domains using clinical science approaches such as cognitive/emotional/behavioral; liquid-based methods; structural/functional imaging); expert in at least one.
- Knowledge of the drug development process and proven integration into clinical translation with a track record advancing multiple assets to POC or beyond.
- Proven leadership directing/leading/learning from cross-functional teams, including leading a team of translational scientists.
- Strong presentation skills to scientists and nonscientists.
Benefits (as stated):
- Comprehensive benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance, and 401(k) for eligible employees.
Additional/Application instructions:
- Not provided in the text.