Scientific Director I, Translational Precision Medicine, Neuroscience
AbbVie
3 months ago
Remote friendly (Waltham, MA)
United States
Clinical Research and Development
Purpose:
- Translational scientist in Precision Medicine Neuroscience bridging basic brain/nervous system research and clinical applications to develop biological and disease insights for neurological and psychiatric disorders.
Responsibilities:
- Uncover neurobiological mechanisms of disease to elucidate patient subtypes, mechanisms of action/response/resistance, and advance novel interventions.
- Develop testable hypotheses about neurobiological pathways, neuronal circuitry, cognitive/behavioral domains, or functional disease/patient-subtype markers; collaborate with PMed DAS leads and other functional leads to execute operationally sound approaches and deliver actionable outcomes.
- Shape and enhance human neuroscience efforts, including promoting R&D synergies aligned to disease area strategic goals.
- Drive scientific strategy for translational biomarker development and discovery target validation/MOA projects.
- Lead design of clinically translational experiments with PMED, clinical leads, and/or discovery research translational teams.
- Establish external collaborations to augment internal efforts and expand experimental design options.
- Ensure quality/effectiveness of major precision medicine project plans through sound design and early risk assessment.
- Advance clinical translational efforts through stakeholder alignment and navigation of emerging business challenges.
- Proactively advise and share knowledge with subordinates, peers, and senior management.
- Source and leverage emerging scientific trends to keep pace with and advance translational neuroscience standards.
Qualifications:
- Bachelor’s degree (Science) with 20 years related work; Master’s degree (Science) with 14 years; or PhD/terminal degree (or PharmD/MD) with 10 years related experience.
- Relevant experience in biology, target validation, and biomarker research in neural circuits and functional domains using clinical science approaches (e.g., cognitive/emotional/behavioral), liquid-based methods, or structural/functional imaging (expert in at least one).
- Knowledge of the drug development process and how clinical translation fits within it.
- Proven track record integrating into drug development and advancing one or more assets.
- Proven leadership directing and learning from cross-functional teams.
- Strong presentation skills to scientists and non-scientists.
Benefits:
- Paid time off; medical/dental/vision insurance; 401(k) (to eligible employees).
Application instructions:
- None provided in the job description text.
- Translational scientist in Precision Medicine Neuroscience bridging basic brain/nervous system research and clinical applications to develop biological and disease insights for neurological and psychiatric disorders.
Responsibilities:
- Uncover neurobiological mechanisms of disease to elucidate patient subtypes, mechanisms of action/response/resistance, and advance novel interventions.
- Develop testable hypotheses about neurobiological pathways, neuronal circuitry, cognitive/behavioral domains, or functional disease/patient-subtype markers; collaborate with PMed DAS leads and other functional leads to execute operationally sound approaches and deliver actionable outcomes.
- Shape and enhance human neuroscience efforts, including promoting R&D synergies aligned to disease area strategic goals.
- Drive scientific strategy for translational biomarker development and discovery target validation/MOA projects.
- Lead design of clinically translational experiments with PMED, clinical leads, and/or discovery research translational teams.
- Establish external collaborations to augment internal efforts and expand experimental design options.
- Ensure quality/effectiveness of major precision medicine project plans through sound design and early risk assessment.
- Advance clinical translational efforts through stakeholder alignment and navigation of emerging business challenges.
- Proactively advise and share knowledge with subordinates, peers, and senior management.
- Source and leverage emerging scientific trends to keep pace with and advance translational neuroscience standards.
Qualifications:
- Bachelor’s degree (Science) with 20 years related work; Master’s degree (Science) with 14 years; or PhD/terminal degree (or PharmD/MD) with 10 years related experience.
- Relevant experience in biology, target validation, and biomarker research in neural circuits and functional domains using clinical science approaches (e.g., cognitive/emotional/behavioral), liquid-based methods, or structural/functional imaging (expert in at least one).
- Knowledge of the drug development process and how clinical translation fits within it.
- Proven track record integrating into drug development and advancing one or more assets.
- Proven leadership directing and learning from cross-functional teams.
- Strong presentation skills to scientists and non-scientists.
Benefits:
- Paid time off; medical/dental/vision insurance; 401(k) (to eligible employees).
Application instructions:
- None provided in the job description text.