Scientific Director

Role Summary

The Translational Safety & Risk Sciences (TSRS) function at Amgen is seeking a Scientific Director to serve as a Project Toxicologist and a Subject Matter Expert, reporting to the Senior Director Head Therapeutic Area Strategy Leaders and Business Development Liaisons.

Responsibilities

• Develop and implement a fit-for-purpose nonclinical safety strategy based on a strong scientific foundation, evolve the strategy in response to team goals and emerging data, and lead multidisciplinary TSRS teams.
• As a project team representative (PTR), partner with project teams developing therapeutics leveraging a variety of modalities (including biotherapeutics, small molecules and RNA therapies) to treat diseases in inflammation, oncology and/or cardiometabolic diseases, including obesity and rare diseases.
• There is potential for opportunities with broader Inflammation and/or Oncology Therapeutic Area responsibilities and to conduct scientific due diligence for business development opportunities in oncology and CMD therapeutic areas.
• PTRs are encouraged to develop subject matter expertise related to a specific modality, therapeutic area, or safety concern.

Qualifications

• Required: Doctorate degree in Toxicology or a related scientific field, and 4 years of experience OR
• Required: Master’s degree and 7 years of experience OR
• Required: Bachelor’s degree and 9 years of experience
• Required: Excellent and professional communicator; proven ability to influence a broad spectrum of partners toward achieving business goals
• Preferred: A minimum of 10 years of drug development experience, at all stages of development including late-stage assets and interactions with global regulatory agencies for IND/CTA and NDA/BLA filings
• Preferred: Expertise in the field of immunology, either through immune-toxicology, immune-oncology or immunology related drug-target support.
• Preferred: End-to-end small and large molecule safety assessment experience across multiple therapeutic areas and modalities potentially including antibody drug conjugates and T-cell engagers
• Preferred: External visibility as a toxicology expert as demonstrated by a strong external presentation and publication record and leadership of external collaborative groups
• Preferred: Comfortable operating as a cross-functional and inter-functional thought partner on multi-disciplinary teams across R&D functions
• Preferred: Experience supporting business development efforts in the conduct of due diligence evaluations as translational safety team member
• Preferred: Experienced scientific leader with direct or matrixed management experience
• Preferred: Diplomate of the American Board of Toxicology