Research Scientist I/II: Pharmacology
Novartis
June 24, 2026
On-site
Cambridge, MA
Clinical Research and Development
Responsibilities:
- Hands-on execution of pre-clinical in vivo studies to explore novel hypotheses, screen candidate molecules, and establish proof-of-concept.
- Develop in vivo CDX, PDX, and syngeneic models to evaluate anti-tumor activity, PK/PD relationships, and relevant biomarkers of novel compounds to support clinical development.
- Work independently and in collaboration with pharmacology colleagues to execute studies.
- Critically analyze and present results within a multidisciplinary team environment.
- Adhere to animal protocols and properly document data and methods in an electronic laboratory notebook.
Qualifications:
- Research Scientist I: BS/MS in biological sciences with 2+ years of relevant research experience in pharmaceutical/biotech industry.
- Research Scientist II: BS/MS in biological sciences with 4+ years of relevant research experience in pharmaceutical/biotech industry.
- Extensive experience with CDX/PDX xenograft tumor models and/or syngeneic models.
- Experience with cell culture.
- Hands-on mouse/rat handling skills, including dosing (IV, IP, PO), tumor implantation, caliper tumor measurements, xenogen imaging, and blood/tissue collection.
- Experience with PCR, ELISA, western blot, and flow cytometry.
- Strong analytical, written/verbal communication, and organizational skills; proficiency with PowerPoint and data analysis tools (e.g., Excel, Prism).
- Hands-on execution of pre-clinical in vivo studies to explore novel hypotheses, screen candidate molecules, and establish proof-of-concept.
- Develop in vivo CDX, PDX, and syngeneic models to evaluate anti-tumor activity, PK/PD relationships, and relevant biomarkers of novel compounds to support clinical development.
- Work independently and in collaboration with pharmacology colleagues to execute studies.
- Critically analyze and present results within a multidisciplinary team environment.
- Adhere to animal protocols and properly document data and methods in an electronic laboratory notebook.
Qualifications:
- Research Scientist I: BS/MS in biological sciences with 2+ years of relevant research experience in pharmaceutical/biotech industry.
- Research Scientist II: BS/MS in biological sciences with 4+ years of relevant research experience in pharmaceutical/biotech industry.
- Extensive experience with CDX/PDX xenograft tumor models and/or syngeneic models.
- Experience with cell culture.
- Hands-on mouse/rat handling skills, including dosing (IV, IP, PO), tumor implantation, caliper tumor measurements, xenogen imaging, and blood/tissue collection.
- Experience with PCR, ELISA, western blot, and flow cytometry.
- Strong analytical, written/verbal communication, and organizational skills; proficiency with PowerPoint and data analysis tools (e.g., Excel, Prism).