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Research Scientist & Cell Assay Specialist

Vanda Pharmaceuticals
Full-time
Remote friendly (Washington, DC)
United States
Clinical Research and Development

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Role Summary

Research Scientist & Cell Assay Specialist. Develops and designs multiple assays for screening biological targets, analyzes data from biomarker and characterization assays, and supports research projects with laboratory duties, compliance, and documentation.

Responsibilities

  • Maintains cell line cultures (growth, extraction of specimens)
  • Prepares specimens for analysis; aliquots, transports and distributes specimens
  • Maintains tracking information for specimens
  • Coordinates prioritization, receipt and delivery of laboratory specimens
  • Verifies accurate documentation relative to specimen processing
  • Accepts or rejects specimens according to established standards and performs specimen investigation procedures to resolve lab specimen issues or problems
  • Runs RNA and protein assays with necessary troubleshooting
  • Demonstrates an understanding of the theory and scientific principles of laboratory testing as well as the technical, procedural and problem-solving aspects
  • Performs and interprets tests at all complexity levels
  • Correlates abnormal laboratory data with pathological states, determines the validity of test results and the need for additional tests
  • Determines the validity of test results through the monitoring and/or verifying of quality controls, standards, etc
  • Communicates test results, reference ranges, specimen requirements, and other pertinent information to authorized sources
  • Assumes responsibility for good documentation practices and maintains clear and legible records
  • Accumulates data from analyses, prepares charts, graphs, statistical tables for presentation to Research Staff Supervisor for final analysis
  • The successful candidate will assist with general lab duties, protocols and compliance responsibilities, and will be proactively involved in assigned research
  • Maintains instrumentation and equipment along with its cleanliness
  • Performs preventive maintenance and record keeping procedures
  • Maintains appropriate workstation supplies and inventory
  • Develops and designs multiple assays for screening in-vitro and in-vivo biological targets
  • Collects and interprets data for biomarker and biological characterization assays including cell-based, multiplexed protein assays, polymerase chain reaction and flow cytometry methods
  • Develops biochemical assays for lead validation and optimization for disease-related targets to predict outcome in supporting development by enabling earlier decision making, reducing investment risk and avoiding late phase failures
  • Emphasis may be development of biochemical assays for high throughput screening. May oversee screening operations, including scheduling, assay performance and data flow
  • May work with manufacturing and quality control to develop tests, as well as analyze and report results
  • Prepares technical reports, summaries, protocols and quantitative analyses

Qualifications

  • Bachelor’s degree in chemical, physical, biological or clinical laboratory science or medical technology preferred; Master's degree preferred
  • Minimum of two years of progressive lab experience (independent/leading role preferred); 5+ years preferred
  • Typical physical demands include visual acuity and the ability to distinguish colors; manual dexterity to handle specimens diagnose/troubleshoot equipment; may require extended periods of sitting, standing and walking, light lifting may be required

Education

  • Bachelor’s degree in chemical, physical, biological or clinical laboratory science or medical technology preferred; Master's degree preferred

Additional Requirements

  • Must be able to perform the essential functions of the position, with or without reasonable accommodation