Research Associate - RNA Synthesis Platform Development
Sanofi
August 29, 2026
On-site
Waltham, MA
$64,500 - $93,166.66 USD yearly
Clinical Research and Development
Main Responsibilities:
- Support individual program development using platform synthesis technologies.
- Evaluate and develop new technologies to improve current RNA synthesis platform processes.
- Operate and optimize Hamilton Vantage automated systems and liquid-handling platforms using Venus software.
- Design and execute enzymatic reactions focused on in vitro transcription (IVT) and enzyme kinetics.
- Perform nucleic acid purification and characterization using advanced analytical techniques.
- Design experiments and conduct quantitative data analysis to drive scientific conclusions.
Basic Qualifications:
- Bachelor’s degree in Biochemistry, Molecular Biology, Chemical Engineering, or related field.
- 1+ years of hands-on experience in an industrial laboratory setting.
Additional Qualifications / Required Skills:
- Strong background in enzymatic reactions and catalysis, especially IVT reactions and enzyme kinetics.
- Demonstrated RNA synthesis and enzymatic process development experience (preferably for mRNA manufacturing).
- Experience with Hamilton Vantage automated systems and Venus software for liquid handling.
- Proficiency in RNA purification and characterization assays: ethanol precipitation, spectrophotometry, capillary electrophoresis, ELISA, and qPCR.
- Strong experimental design and quantitative data analysis skills.
- Fluency in English (written and verbal); detail-oriented, organized, collaborative, and adaptable.
Benefits (if applicable):
- Health and wellbeing benefits, including at least 14 weeks’ gender-neutral parental leave.
Compensation:
- Determined commensurate with demonstrated experience; employees may be eligible for company employee benefit programs.
- Support individual program development using platform synthesis technologies.
- Evaluate and develop new technologies to improve current RNA synthesis platform processes.
- Operate and optimize Hamilton Vantage automated systems and liquid-handling platforms using Venus software.
- Design and execute enzymatic reactions focused on in vitro transcription (IVT) and enzyme kinetics.
- Perform nucleic acid purification and characterization using advanced analytical techniques.
- Design experiments and conduct quantitative data analysis to drive scientific conclusions.
Basic Qualifications:
- Bachelor’s degree in Biochemistry, Molecular Biology, Chemical Engineering, or related field.
- 1+ years of hands-on experience in an industrial laboratory setting.
Additional Qualifications / Required Skills:
- Strong background in enzymatic reactions and catalysis, especially IVT reactions and enzyme kinetics.
- Demonstrated RNA synthesis and enzymatic process development experience (preferably for mRNA manufacturing).
- Experience with Hamilton Vantage automated systems and Venus software for liquid handling.
- Proficiency in RNA purification and characterization assays: ethanol precipitation, spectrophotometry, capillary electrophoresis, ELISA, and qPCR.
- Strong experimental design and quantitative data analysis skills.
- Fluency in English (written and verbal); detail-oriented, organized, collaborative, and adaptable.
Benefits (if applicable):
- Health and wellbeing benefits, including at least 14 weeks’ gender-neutral parental leave.
Compensation:
- Determined commensurate with demonstrated experience; employees may be eligible for company employee benefit programs.