Research Associate II / Senior Research Associate, Bioanalytical

Role Summary

Research Associate II / Senior Research Associate, Bioanalytical role focused on supporting bioanalytical sample analysis for early discovery and development programs. The position involves evaluating and optimizing bioanalytical methods to measure drug concentrations in various biological matrices, collaborating with cross-functional teams, and supporting quantification of oligonucleotides, bioconjugates, peptides/antibodies, and gene editing samples using ligand binding assays. The role requires independent data analysis, creation of data summary reports, and effective communication with study teams and external laboratories.

Responsibilities

• Support bioanalytical sample analysis activities for both early discovery and development programs by evaluating, developing/ optimizing bioanalytical methods for measurement of drug concentrations in a variety of biological matrices (ex. plasma, tissue).
• Work with cross-functional teams supporting analysis of molecules consistent with the development project objectives.
• Support oligonucleotide, bioconjugate and peptide/antibody quantification, gene editing sample analysis using ligand binding assays
• Analyze samples independently and create data summary reports based on collected data to the study teams and project leads
• Communicate and facilitate research assay transfer and troubleshooting at external laboratories and CROs as needed.
• Day-to-day activities include in-lab sample analysis, assay optimization and/ or troubleshooting of complex assays for LBA (ELISA, ECL), and as needed Immunogenicity (ADA) assays.

Qualifications

• Required: B.S./ M.S. in Analytical Chemistry, Biochemistry, Biology, or equivalent.
• Required: At least 3 - 5 years of biotech research, analytical or bioanalytical experience
• Required: Significant knowledge and hands-on experience with ligand binding and/ or RT-PCR assays; Mass spectrometry experience a plus
• Required: Experience with oligonucleotide, protein, peptide analysis is a plus.
• Required: Ability to solve complex scientific assay and project-based problems efficiently and constructively using independent thinking.
• Required: An ability to be productive and successful in an intense work environment
• Required: Strong analytical skill sets and outstanding verbal and written communication skills.

Education

• B.S./ M.S. in Analytical Chemistry, Biochemistry, Biology, or equivalent.