Position Summary
The Research Associate II will assist with the discovery, research, and development of immunotherapies across multiple therapeutic areas, supporting experiments to generate plasmid DNA and mRNA for R&D and troubleshooting efficient production of recombinant DNA/RNA for Antibody Discovery, Vaccine Development, NK/T-Cell Therapeuties, and CAR Development.
Essential Functions
- DNA cloning (PCR, restriction digests, plasmid assembly, bacterial transformations, plasmid purifications)
- Maintain records of constructs (sequences, raw reads, QC results, stock inventory)
- In vitro transcription and RNA purifications
- Contribute to in vitro selection experiments
- Protein expression (mammalian cell culture and bacterial expression)
- Protein purification (affinity chromatography)
- Train junior personnel on basic molecular biology techniques
- Support lab duties; follow and recommend SOPs/process improvements
- Perform ad-hoc/cross-functional projects supporting business needs
Education & Experience / Requirements
- Bachelorβs in a scientific discipline + 2+ years industry OR Masterβs + some industry experience
- Molecular biology: oligo design, PCR, mutagenesis, cloning, data analysis, in vitro transcription/RNA production
- Protein expression in mammalian and bacterial systems
- In vitro selection techniques (preferred)
Knowledge, Skills, Abilities
- Self-starter; fast-paced and flexible; plan/perform experiments with minimal guidance
- Troubleshoot independently; analyze data; prepare presentations
- Organized lab notebook (IND-enabling studies), use electronic/lab inventories
- Ship/receive reagents; keep organized reagent records; MS Office proficiency; collaborative
Benefits (eligible)
- Medical, Dental, Vision; Wellness programs; EAP; Life/AD&D; Short/Long-term disability
- Healthcare/Dependent Care FSAs; 401(k) match; 529; PTO (incl. 11 holidays)
- Exempt: Unlimited PTO; Non-exempt: 10 vacation days, 56 health hours, 2 personal, 1 cultural day
Compensation & Application
- Discretionary bonus and equity; base pay range: $81,000β$89,100 annually
- Application window: anticipated 60 days from posting (or sooner if filled/closed).