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Job Description

OBJECTIVE

Responsible for supporting the cell line development (CLD) team through participation in transfection, stable selection, cloning, expansion, characterization of mammalian cell lines for clinical and commercial production, as well as automation, data processing and digitalization. This position will perform laboratory experiments using a variety of CLD and cell culture technologies including single cell cloning/clone picking, cell imaging, liquid handling automation and Octet/ELISA-based recombinant protein quantification. The candidate will need strong organizational skills and experience with a variety of data and digital tools for review and interpretation of data and its use in models to improve CLD outcomes. Programming skills with Python, R, etc. is a plus. This position will be expected to conduct experiments with supervision, document experimental steps in an electronic laboratory notebook, and draft support documentation.

ACCOUNTABILITIES

• Familiar with molecular biology and cell culture techniques, previous CHO cell line development experience is appreciated.
• Familiar with general laboratory procedures and aseptic technique.
• Contributes directly to project work which may include multiple projects within functional area and presents data in group meetings.
• Identifies technical issues and implements solutions under supervision.
• Supports technology development projects as well as cell line development for pipeline molecules under supervision.
• Prepares experimental protocols and keeps good records of experiments.
• Coordinates within department as well as cross functionally with peers on projects.
• Experience with data and digital applications and programing language will be a plus.
• Experience with automation, FACS, ddPCR and Next-Gen Sequencing will be a plus.

EDUCATION, EXPERIENCE AND SKILLS

• Bachelor’s degree in biochemistry, molecular biology, biotechnology, or related pharmaceutical science; 1+ years of biotechnology/biopharmaceutical industry experience, preferably in cell line development.
• Master’s degree in biochemistry, molecular biology, biotechnology, or related pharmaceutical science.

Knowledge and Skills

• Learning Skills: Able to learn different procedures under supervision or from protocols, has attention to details to identify and solve problems.
• Teamwork: Ability to work within department groups/team.
• Communication Skills: Expresses oneself clearly and concisely within function; documents issues and/or concerns concisely with colleagues; timely and effectively communicates issues to supervisor.
• Organization: Exercises good time management skills.
• Technical: Proficient in use of applicable lab equipment and operations.

Physical Demands

Cell culture technique does involve some repetitive motion.

LINE FUNCTION SPECIFIC QUALIFICATIONS

• Biologics – Upstream Process Development Cell line development:
• Sound knowledge of cell culture principles, experience in aseptic techniques required.
• Experience in CLD technologies including culture of mammalian cells, single cell cloning (sorting/clone picking), clonality assessment, and clone screening highly desirable.
• Experience in molecular biology methods including subcloning, northern blot, RT-qPCR/ddPCR and Octet/ELISA-based recombinant protein quantification is desirable.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location

Boston, MA

U.S. Hourly Wage Range

$26.92 - $42.31

The estimated hourly wage range reflects an anticipated range for this position. The actual hourly wage offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual hourly wage offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job Exempt

No

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.