Role Summary
Research Associate reporting to the Scientist I/II and working with the Senior Research Associate I/II to execute and analyze lab-based and small animal experiments. This role involves exposure to multiple facets of research operations including program discovery and development.
Responsibilities
- Executing and analyzing small animal experiments to evaluate immune responses to various antigen and adjuvant combinations (murine handling, injections, blood/organ collections, ex vivo tissue preparation and analysis)
- Executing and analyzing small animal experiments to evaluate anti-tumor activity of immunotherapy candidates (murine handling, tumor injections and monitoring, blood/organ collections, ex vivo tissue preparation and analysis)
- Executing assays to assess mechanisms of action underlying therapeutic activity
- Maintaining detailed and accurate records, data graphing and presentation
- Communicating findings in various forums both intra- and interdepartmentally
- Highly productive and comfortable in a fast-paced work environment
Education
- Bachelorβs degree in biology or related discipline
Skills
- Murine handling techniques and injections
- Sample collection and processing: blood, spleen, lymph nodes, tumor, etc
- Experience with murine syngeneic tumor models
- Execution of ex vivo immuno-assays: multi-color flow cytometry, ELISpot/FluoroSpot, ELISA, Luminex, etc
- Tissue culture (cell culture and aseptic technique, isolation of splenocytes or lymphocytes from murine samples)
- Hands on experience with in vitro human immune cell assays a plus
- Familiarity with pre-clinical drug development a plus
Additional Requirements
- Travel: Frequent travel to animal facility required (within 3 miles of Elicio office)
- Physical Requirements: Subject to periods of sitting or standing, vision is required to monitor data
- Work Location: Onsite only