Regional Business Director, US Central

Join our team in a dynamic hybrid role, offering flexibility to work remotely and from our headquarters in Watertown, MA.

COMPANY OVERVIEW:

Disc Medicine is a clinical-stage biopharmaceutical company committed to discovering, developing, and commercializing novel treatments for patients who suffer from serious hematologic diseases. We are building a portfolio of innovative, first-in-class therapeutic candidates that aim to address a wide spectrum of hematologic diseases by targeting fundamental biological pathways of red blood cell biology, specifically heme biosynthesis and iron homeostasis. Disc Medicine values collaboration, professional development, and scientific integrity and promotes an inclusive company culture that empowers and inspires.

POSITION OVERVIEW:

As a Regional Business Director (RBD) at Disc Medicine, you will be responsible for strategically building a high performing sales team to execute on our U.S. commercial launch strategy. Reporting to the Vice President of Sales, you will oversee Salesforce-enabled lead programs, and ensure compliant, science-driven customer engagement that enables Disc Medicine to successfully achieve forecasted patient demand.

This is a unique opportunity to help establish a best-in-class field commercial model at a pivotal moment for a patient-first, scientifically rigorous organization. Success in this role requires strong scientific acumen, the ability to lead through data, and a passion for translating innovation into impact for patients.

This position will lead our central US region which includes mid-west and southeast states. Candidates should reside within the assigned region.

RESPONSIBILITIES:

• Identify, recruit, lead, and develop a regional team of Rare Disease Specialists, providing strategic guidance and support to drive sales and engagement goals while fostering a culture of scientific credibility and integrity.
• Drive field execution of the national sales strategy, ensuring alignment with patient demographics, referral pathways, and centers of excellence.
• Achieve or exceed regional revenue targets following product launch, ensuring strategic execution of commercial plans to drive performance.
• Collaborate with Sales Operations and Training to enhance CRM adoption and optimize reporting tools and dashboard functionality.
• Clearly communicate, reinforce and oversee regional implementation of Salesforce workflows, including lead generation, call planning, documentation, and pipeline management, to support effective field execution and data-driven decision-making.
• Coordinate the development and analysis of territory and regional performance metrics to continuously refine strategy and improve results. Utilize market insights and collaborate cross-functionally to maximize sales opportunities and drive long-term business growth.
• Partner cross-functionally with Marketing, Medical Affairs, Market Access, and Patient Services to deliver coordinated, aligned HCP engagement.
• Serve as the field voice to headquarters—sharing customer insights, competitive intelligence, and market trends.
• Represent the company at national and regional conferences and launch meetings.
• Ensure compliance with all relevant regulations and policies (e.g., Sunshine Act, FDA promotional guidelines, PhRMA guidelines, Open Payments).
• Champion Disc Medicine's values of scientific rigor, patient-focus, ethical integrity, and team collaboration.
• Engage and inspire employees to create a culture that fosters an inclusive, high-performing team culture grounded in accountability, partnering, learning, and support.

REQUIREMENTS:

• Bachelor's degree required; advanced degree (MBA, MS, PhD) preferred.
• Minimum of 12 years of commercial sales experience in the pharmaceutical or biotech industry, including at least 3 years in a leadership role in regional or national sales, market access, and/or marketing.
• Proven experience in patient identification and pull-through, utilizing established relationships with dermatologists and hematologists.
• Demonstrated disease and startup biotech environments. Hematology and/or Dermatology experience preferred.
• Success in building and scaling field organizations, particularly in rare disease.
• Experience launching early-stage therapies or building commercial infrastructure for pre-commercial products is strongly preferred.
• Strong scientific acumen with the ability to interpret clinical data, lead scientifically credible teams, and engage confidently with healthcare professionals.
• Deep understanding of CRM, lead funnel management, territory planning, and call execution.
• Solid understanding of payer landscape, patient-access programs, and reimbursement models in rare disease treatment.
• Data-driven mindset with the ability to interpret and act on regional performance analytics.
• Exceptional leadership, coaching, and interpersonal communication skills.
• High emotional intelligence with the proven ability to lead remote teams and build cross-functional trust.
• Sound knowledge of compliance frameworks, including the Sunshine Act, HIPAA, and FDA promotional regulations.
• Organized, self-motivated, and effective in dynamic, rapidly evolving commercial settings.

Disc Medicine is an equal-opportunity employer committed to providing all qualified candidates and employees equal opportunities. We offer comprehensive benefits and competitive compensation packages. The Company headquarters are in Watertown, MA, and we provide a flexible work environment.

Disc Medicine actively recruits individuals with an entrepreneurial spirit and a drive for excellence. Interested candidates should submit a cover letter and resume to be considered for current and future opportunities.