Real World Evidence Manager

Role: The Real World Evidence (RWE) Manager supports epidemiologic and observational research to assess disease natural history and real-world outcomes for Vertex's pipeline and portfolio. Responsibilities include designing and executing epidemiologic studies, ensuring scientific rigor, managing vendors, and supporting internal stakeholders such as Clinical Development, Medical Affairs, and Regulatory teams. The role involves developing research strategies, analyzing relevant data sources, and communicating key findings through publications and presentations. Qualifications: PhD (preferred) or MS/MPH in epidemiology, biostatistics, or health outcomes research, with at least 2 years' experience in observational research within the life sciences industry or relevant academic/government settings. Skills include expertise in study design, familiarity with RWE regulatory guidance, interpersonal and project management skills, and ability to translate complex data into clear insights. High-Value Details: Focus on observational research supporting biopharma pipeline, with emphasis on natural history studies and systematic literature reviews; experience with regulatory considerations in RWE; hybrid or onsite work setup; no specific therapeutic area or modality specified.