PSP Data Governance & Cross Program Analytics, Senior Manager

Job Description General Summary Vertex is seeking a Senior Manager, PSP Data Governance & Cross‑Program Analytics to operationalize and mature enterprise data governance frameworks and tools within the Patient Support organization, while enabling cross‑program analytics that drive consistent, high‑quality decision‑making. This role will apply enterprise governance standards to PSP‑specific data sources, including CRM platforms, vendor feeds, and PHI-enabled reporting environments. The Senior Manager will establish stewardship models, define data standards and controls, owning data classification, and drive accountability to ensure compliant, trusted, and analytics‑ready data—enabling scalable reporting and integrated insights across patient support programs. Additionally, this role will lead cross‑program analytics execution, delivering standardized KPIs, dashboards, and performance insights that support operational excellence across the patient support organization. The ideal candidate brings data governance experience, analytical rigor, and the ability to influence cross‑functional partners in a complex, matrixed environment. Key Duties and Responsibilities Operationalize the enterprise data governance framework and process within Patient Support by establishing PSP‑specific data standards, definitions, controls, documentation, and data quality rules to ensure consistent, compliant, and scalable use of data across programs. Lead collaboration with data domain owners, data stewards and data custodians to drive adoption of governance policies. Provide oversight and accountability for data quality management across PSP data sources, including CRM systems and vendor feeds. Establish and maintain end‑to‑end traceability for priority patient support metrics (source → transformation → KPI → dashboard), enabling transparency, auditability, and leadership confidence in reported insights. Lead cross‑program analytics execution, including the development and maintenance of standardized KPIs, dashboards, and scorecards that support consistent reporting and insight generation. Partner with Patient Support CoE teams (Program Quality, Systems, Vendor Management) to align analytics and governance efforts with operational priorities and broader program strategies. Partner with Legal and Privacy teams to operationalize analytics guardrails and access controls, ensuring outputs adhere to consent, data minimization, and purpose‑of‑use policies. Communicate insights to program and brand leadership, influencing data‑driven decision‑making across the organization. Knowledge and Skills Demonstrated expertise leading data quality and data governance initiatives while successfully influencing cross-functional stakeholders. Demonstrated process design and documentation skills, with experience establishing data standards and governance workflows. Proven ability to synthesize complex data, identify key trends, and translate insights into actionable recommendations. Strong data storytelling and communication skills, translating analytical insights into clear, compelling narratives for cross‑functional and mid‑level leadership. Advanced analytical expertise with proficiency in Excel, SQL, and Power BI. Demonstrated ability to leverage AI tools to speed analytic development Knowledge of data management tools and software, (e.g. Snowflake and Collibra or similar tools). Highly flexible, comfortable navigating ambiguity and thriving in a fast‑paced, dynamic environment. Education and Experience Bachelor’s degree in a quantitative discipline (e.g. Data Science, Information Systems, Computer Science, Data Management, Healthcare Analytics, or related field). 6+ years of experience in data governance, data quality and/or commercial analytics. Demonstrated experience leading cross‑functional initiatives and driving operational excellence through data. Pay Range: $137,600 - $206,400 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com Help Us Achieve Our Mission Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has approved medicines that treat the underlying causes of multiple chronic, life-shortening genetic diseases — cystic fibrosis, sickle cell disease and transfusion-dependent beta thalassemia — and continues to advance clinical and research programs in these diseases. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including APOL1-mediated kidney disease, acute and neuropathic pain, type 1 diabetes, myotonic dystrophy type 1 and alpha-1 antitrypsin deficiency . Founded in 1989 in Cambridge, Mass., Vertex's global headquarters is now located in Boston's Innovation District and its international headquarters is in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 14 consecutive years on Science magazine's Top Employers list and one of Fortune’s 100 Best Companies to Work For. For company updates and to learn more about Vertex's history of innovation, visit www.vrtx.com or follow us on Facebook, Twitter/X , LinkedIn, YouTube and Instagram. The diversity and authenticity of our people is part of what makes Vertex unique, and we recognize that each employee brings diverse perspectives and strengths. By embracing those strengths and celebrating differences, we are fostering an inclusive culture where each of us can bring our authentic selves to work, inspire innovation together, and change people’s lives. Our vision is clear: to be the place where an authentic, diverse mix of talent want to come, to stay, and do their best work.