Process Development Associate - Pilot Scale Purification Development

Role Summary

Regeneron's Preclinical Manufacturing & Process Development Group (PMPD) is seeking a Process Development Associate as a full-time position to work in the Purification Development group. In this role, you will be responsible for the purification at pilot scale of a variety of clinical biologics, building systems to support the planning and execution of pilot scale work, and investigating technologies to support the scalability of pilot scale operations. The ideal candidate will be hardworking, efficient, flexible, and able to perform key responsibilities in a fast-paced, team environment. This is a lab-based role focused on pilot scale operations, requiring a significant amount of physical activity.

Responsibilities

• A typical day includes operating in a laboratory setting, managing and organizing data more independently, and working under supervision; executing experiments alone and/or in collaboration; presenting results to the supervisor; designing experiments with proper controls.
• Execute experiments/projects using established procedures, perform basic data entry and analysis, interpret data, and compare internal results with literature as directed.
• Read and understand scientific literature and technical documentation; execute experimental plans to verify findings and prepare data for review with the manager.
• Train and become proficient in operation of laboratory instrumentation and data systems; participate in knowledge/data management and maintenance of lab/data resources; assist in training new staff after demonstrating competency.
• Support technology development and improvement initiatives; contribute to development of technology and automation to increase throughput and speed of pilot scale operations.
• Build relationships within the subgroup to support shared goals; train peers and assist co-op students/interns; proactively help others in execution of experiments and know when to ask for help.

Qualifications

• Required: 1-5+ years’ experience in the biotech or pharmaceutical industry; strong fundamental understanding of protein purification techniques.
• Preferred: Experience with Downstream Development and with equipment such as tangential flow filters, normal flow filters, ultrafiltration/diafiltration skids, Akta chromatography systems, disc stack centrifuge, depth filtration, chromatographic columns, HPLC/UPLC, Empower, Unicorn, JMP, LIMS, PI Historian; Raman spectroscopy and/or software programming.

Education

• Bachelor’s and/or Master’s degree in Chemical Engineering, Biochemical Engineering, or Biochemistry.

Additional Requirements

• Physical demands: this is a lab-based role requiring a significant amount of physical activity.
• On-site work requirements and related expectations may vary by location.