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Principal Systems Engineer, Digital Lab Systems

Moderna
August 19, 2026
Full-time
Remote friendly (Norwood, MA)
Worldwide
IT
Role: Principal Systems Engineer, Digital Lab Systems, supporting laboratory automation in a biopharma QC environment. Responsibilities: lead design, deployment, and optimization of automated workflows using Hamilton liquid handling platforms; develop integrated automation solutions with data pipelines, APIs, and middleware; troubleshoot complex systems, ensure compliance with GLP/GCLP, and support lifecycle management; mentor colleagues and collaborate with vendors on system upgrades and strategy. Requirements: Bachelor's or master's in engineering, Computer Science, Biotechnology, or related field; 8+ years in laboratory automation with experience in Hamilton platforms, system integration (REST, APIs), programming (Python, Java, C++), and data management; familiarity with AI/ML applications and regulated environments. Preferred: experience with web services, GxP compliance, and agile methodologies. High-Value: biopharma QC, laboratory automation, sample management, GCLP/GLP, digital lab transformation, automation troubleshooting, and integration; focus on enhancing efficiency, data integrity, and system reliability. WorkSetup: not specified; likely on-site given lab automation context.