Principal/Sr. Principal Scientist - Molecular Biology, Cell Culture Upstream Process Development
Eli Lilly and Company
2 months ago
On-site
Indianapolis, IN
$65,250 - $169,400 USD yearly
Operations
Principal Scientist / Sr. Principal Scientist (Bioproduct Research & Development)
Responsibilities:
- Design and execute upstream development experiments for bioproduct active pharmaceutical ingredients (including protein intermediates for bioconjugation).
- Provide hands-on troubleshooting support and drive innovation projects using novel ideas and technologies.
- Participate in cross-functional process development teams and collaborate across BR&D, Discovery, Technical Services for Manufacturing, and Manufacturing.
- Support transfer of upstream processes to pilot plant and manufacturing sites.
- Author technical reports and regulatory documents.
- Work with external parties on development projects, research collaborations, and outsourcing.
- Keep current of relevant scientific literature, new technologies/capabilities, and regulatory initiatives/requirements; support implementation.
- Ensure work aligns with Development Quality, Regulatory, HSE, GLP, and GMP requirements.
Basic Requirements:
- BS/MS in Microbiology, Cell Biology, Molecular Biology, Biology, Chemical Engineering, or related field.
- BS with >6 years or MS with >3 years of relevant industrial experience.
- Ability to work well in a team environment; desire to be a point of accountability.
- Effective oral/written communication; self-management, task planning, and organization.
- Authorized to work in the United States full-time; Lilly does not sponsor work authorization or visas.
Additional Skills & Preferences:
- Experience designing experiments, generating data, interpreting results, and documenting work independently.
- Knowledge of cell biology/cell culture/molecular biology with emphasis on recombinant protein expression.
- Hands-on experience with cell line generation and cell culture bioreactor operations.
- Understanding of scaling upstream processes; statistical data analysis.
- Ability to solve problems with minimal supervision; productive interdisciplinary teamwork.
Compensation/Benefits (if applicable):
- Anticipated wage: $65,250 - $169,400.
- Potential company bonus (for full-time equivalent employees).
- Comprehensive benefits including 401(k), pension, vacation, medical/dental/vision, prescription drug benefits, flexible benefits, life insurance, time off/leave of absence, and well-being benefits.
Responsibilities:
- Design and execute upstream development experiments for bioproduct active pharmaceutical ingredients (including protein intermediates for bioconjugation).
- Provide hands-on troubleshooting support and drive innovation projects using novel ideas and technologies.
- Participate in cross-functional process development teams and collaborate across BR&D, Discovery, Technical Services for Manufacturing, and Manufacturing.
- Support transfer of upstream processes to pilot plant and manufacturing sites.
- Author technical reports and regulatory documents.
- Work with external parties on development projects, research collaborations, and outsourcing.
- Keep current of relevant scientific literature, new technologies/capabilities, and regulatory initiatives/requirements; support implementation.
- Ensure work aligns with Development Quality, Regulatory, HSE, GLP, and GMP requirements.
Basic Requirements:
- BS/MS in Microbiology, Cell Biology, Molecular Biology, Biology, Chemical Engineering, or related field.
- BS with >6 years or MS with >3 years of relevant industrial experience.
- Ability to work well in a team environment; desire to be a point of accountability.
- Effective oral/written communication; self-management, task planning, and organization.
- Authorized to work in the United States full-time; Lilly does not sponsor work authorization or visas.
Additional Skills & Preferences:
- Experience designing experiments, generating data, interpreting results, and documenting work independently.
- Knowledge of cell biology/cell culture/molecular biology with emphasis on recombinant protein expression.
- Hands-on experience with cell line generation and cell culture bioreactor operations.
- Understanding of scaling upstream processes; statistical data analysis.
- Ability to solve problems with minimal supervision; productive interdisciplinary teamwork.
Compensation/Benefits (if applicable):
- Anticipated wage: $65,250 - $169,400.
- Potential company bonus (for full-time equivalent employees).
- Comprehensive benefits including 401(k), pension, vacation, medical/dental/vision, prescription drug benefits, flexible benefits, life insurance, time off/leave of absence, and well-being benefits.