Principal Scientist, Upstream Process Development

Role: Principal Scientist leading upstream biologics process development within Biologics Process R&D, focusing on cell culture optimization for early- and late-stage clinical and commercial manufacturing. Responsibilities: direct development of high-yield, scalable, robust cell culture processes; provide technical guidance for process characterization, regulatory filings, and technology transfer; drive process innovation and assess new technologies through collaborations; mentor junior staff and contribute to external scientific dissemination. Requirements: Ph.D. in Chemical Engineering, Bioengineering, Biochemistry, or related field with 6+ years or Master's with 8+ years industry experience; proven expertise in CHO fed-batch culture, bioreactor operations, and downstream understanding; strong publication record; familiarity with process development, scale-up, and regulatory processes. Preferred: experience with advanced cell culture modalities such as intensified inoculum, perfusion, high throughput microbioreactors; expertise in data science (metabolic flux, omics, machine learning) and PAT tools; cross-functional team leadership. HighValue: biologics, cell culture process development, upstream platform strategy, late-stage process transfer, and regulatory support for biologics pipeline. Collaboration: working with academia, vendors, and industry partners. WorkSetup: hybrid or on-site with 10% travel. Focus on scientific leadership, innovation, and external scientific contributions.