Principal Scientist – Surface Biology Early Validation Lead
Amgen
5 months ago
Remote friendly (Thousand Oaks, CA)
United States
Clinical Research and Development
Principal Scientist – Surface Biology Early Validation Lead
What You Will Do
- Provide scientific and operational leadership for a team supporting early target validation
- Lead the design and execution of cell-based and quantitative assays to discover and evaluate membrane protein biology
- Establish robust, scalable workflows to support multiple discovery programs
- Interpret experimental data and communicate clear, actionable insights to project teams
- Partner with cross-functional stakeholders across Discovery Sciences and Advanced Technologies and AI, Therapeutic Discovery, and Therapeutic Areas
- Collaborate across teams to integrate data and inform target evaluation and prioritization
- Identify and implement new technologies to enhance assay robustness and throughput
- Mentor and develop scientists, fostering a culture of rigor, collaboration, and accountability
Basic Qualifications
- Doctorate degree and 3 years of scientific experience OR
- Master’s degree and 7 years of scientific experience OR
- Bachelor’s degree and 9 years of scientific experience OR
- Associate’s degree and 12 years of scientific experience OR
- High school diploma/GED and 14 years of scientific experience
- Plus: minimum of 3 years of experience directly managing people and/or leadership experience leading teams, projects, programs, or directing allocation of resources (managerial may run concurrently)
Preferred Qualifications
- PhD in Cell Biology, Molecular Biology, or related discipline
- 5+ years of relevant industry experience, including leadership of scientific projects or teams
- Strong track record in cell-based assay development and early target validation
- Experience working with membrane proteins or receptor biology
- Demonstrated ability to collaborate across functions to support discovery programs
- Strong communication, organization, and problem-solving skills
Benefits (Total Rewards Plan, if eligible)
- Health and welfare plans (medical, dental, vision, life and disability), financial plans, retirement and savings plan (with company contributions), work/life balance, career development
- Discretionary annual bonus (or sales-based incentive for field sales)
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models where possible (per work location type)
Application Instructions
- Apply now via careers.amgen.com; no application deadline—applications continue until a sufficient number are received or a candidate is selected.
What You Will Do
- Provide scientific and operational leadership for a team supporting early target validation
- Lead the design and execution of cell-based and quantitative assays to discover and evaluate membrane protein biology
- Establish robust, scalable workflows to support multiple discovery programs
- Interpret experimental data and communicate clear, actionable insights to project teams
- Partner with cross-functional stakeholders across Discovery Sciences and Advanced Technologies and AI, Therapeutic Discovery, and Therapeutic Areas
- Collaborate across teams to integrate data and inform target evaluation and prioritization
- Identify and implement new technologies to enhance assay robustness and throughput
- Mentor and develop scientists, fostering a culture of rigor, collaboration, and accountability
Basic Qualifications
- Doctorate degree and 3 years of scientific experience OR
- Master’s degree and 7 years of scientific experience OR
- Bachelor’s degree and 9 years of scientific experience OR
- Associate’s degree and 12 years of scientific experience OR
- High school diploma/GED and 14 years of scientific experience
- Plus: minimum of 3 years of experience directly managing people and/or leadership experience leading teams, projects, programs, or directing allocation of resources (managerial may run concurrently)
Preferred Qualifications
- PhD in Cell Biology, Molecular Biology, or related discipline
- 5+ years of relevant industry experience, including leadership of scientific projects or teams
- Strong track record in cell-based assay development and early target validation
- Experience working with membrane proteins or receptor biology
- Demonstrated ability to collaborate across functions to support discovery programs
- Strong communication, organization, and problem-solving skills
Benefits (Total Rewards Plan, if eligible)
- Health and welfare plans (medical, dental, vision, life and disability), financial plans, retirement and savings plan (with company contributions), work/life balance, career development
- Discretionary annual bonus (or sales-based incentive for field sales)
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models where possible (per work location type)
Application Instructions
- Apply now via careers.amgen.com; no application deadline—applications continue until a sufficient number are received or a candidate is selected.