Principal Scientist, Stat. Programming- Early Oncology Development (Hybrid)
Merck
August 22, 2026
Remote friendly (Rahway, NJ)
United States
Clinical Research and Development
Primary Activities:
- Provide technical consultation and analytical support to early development statisticians for exploratory and unplanned statistical analyses
- Address operational challenges requiring strategic solutions across early oncology development
- Support development of programming standards to enable efficient, high-quality production of programming deliverables
- Facilitate global adoption of standards and programming best practices within early oncology
- Pre-process, filter, and manipulate complex data for analyses of molecular biomarker data, imaging data, and external data
- Lead and actively contribute to departmental strategic initiative project teams
Education and Minimum Requirement:
- BA/BS in Computer Science, Statistics, Applied Mathematics, Life Sciences, Engineering or related field + 12+ years SAS/R programming experience in a clinical trial environment; or
- MS in the above fields + 10+ years SAS/R programming experience in a clinical trial environment
Department/Position Required Skills:
- Excellent interpersonal and communication (written/oral/presentation); strong project management and leadership across complex programs
- Superior experience producing R&D deliverables (data, analyses, tables, graphics, listings)
- Significant SAS clinical trial programming expertise (data steps, procedures, SAS/MACRO, SAS/GRAPH)
- Ability to design complex programming algorithms; implement analysis methods not available in commercial software
- Strategic thinking, ability to anticipate stakeholder needs; work across cultures/geographies
- Experience with CDISC and ADaM standards; ensure deliverable quality and process compliance
- Efficient manipulation of very large databases
Preferred Skills:
- Early oncology development; statistical programming standards; process improvement/operational excellence
- Reporting processes (SOPs) and SDLC; Microsoft Project; professional society involvement
- Regulatory submission leadership experience; oncology clinical trial concepts/standards
Application instructions:
- Apply via https://jobs.merck.com/us/en (or Workday Jobs Hub if a current employee). Application deadline is stated on the posting.
- Provide technical consultation and analytical support to early development statisticians for exploratory and unplanned statistical analyses
- Address operational challenges requiring strategic solutions across early oncology development
- Support development of programming standards to enable efficient, high-quality production of programming deliverables
- Facilitate global adoption of standards and programming best practices within early oncology
- Pre-process, filter, and manipulate complex data for analyses of molecular biomarker data, imaging data, and external data
- Lead and actively contribute to departmental strategic initiative project teams
Education and Minimum Requirement:
- BA/BS in Computer Science, Statistics, Applied Mathematics, Life Sciences, Engineering or related field + 12+ years SAS/R programming experience in a clinical trial environment; or
- MS in the above fields + 10+ years SAS/R programming experience in a clinical trial environment
Department/Position Required Skills:
- Excellent interpersonal and communication (written/oral/presentation); strong project management and leadership across complex programs
- Superior experience producing R&D deliverables (data, analyses, tables, graphics, listings)
- Significant SAS clinical trial programming expertise (data steps, procedures, SAS/MACRO, SAS/GRAPH)
- Ability to design complex programming algorithms; implement analysis methods not available in commercial software
- Strategic thinking, ability to anticipate stakeholder needs; work across cultures/geographies
- Experience with CDISC and ADaM standards; ensure deliverable quality and process compliance
- Efficient manipulation of very large databases
Preferred Skills:
- Early oncology development; statistical programming standards; process improvement/operational excellence
- Reporting processes (SOPs) and SDLC; Microsoft Project; professional society involvement
- Regulatory submission leadership experience; oncology clinical trial concepts/standards
Application instructions:
- Apply via https://jobs.merck.com/us/en (or Workday Jobs Hub if a current employee). Application deadline is stated on the posting.