Principal Scientist - Process Translation and Execution Lilly Medicine Foundry

Role: Chemical Process Engineer focused on transferring API/DS processes into clinical supply manufacturing within Lilly’s new Medicine Foundry. Objectives include supporting process scale-up, technology transfer, and phase-appropriate control strategies for modalities like biologics, peptides, oligonucleotides, and bioconjugates. Responsibilities encompass operating and troubleshooting kilo-scale equipment, applying chemical engineering principles to scale-up, developing filtration and crystallization models, evaluating process safety, authoring technical documentation, and executing process validation studies. Qualifications: BS/MS in Chemical Engineering or related discipline; 4+ years industry experience in pharmaceutical process development, pilot plant, or chemical manufacturing; familiarity with GMP, FDA guidelines, and cGMP operations. Preferred skills include hands-on experience with kilo-scale equipment, crystallization development, filtration modeling, and software tools such as Aspen or Dynochem. High-value details: focus on biologics and advanced modalities, transitioning to cGMP production, supporting clinical trial supplies, with initial work based in Indianapolis and eventual permanent role at the Lilly Medicines Foundry in Lebanon, IN. Limited travel (<5%) and work in lab and manufacturing environments required.