Principal Scientist, Neuroscience / Genetic Medicine
Regeneron
August 22, 2026
On-site
Tarrytown, NY
Clinical Research and Development
Responsibilities:
- Design experiments to evaluate efficacy, target engagement, and delivery efficiency of viral and non-viral therapeutic candidates across CNS disease models
- Design AAV transgene cassettes to optimize therapeutic efficacy
- Lead a team of associates in executing experiments and analyzing primary data
- Interpret complex datasets and integrate findings with scientific literature to propose data-driven next steps
- Communicate project strategy, scientific vision, and data updates to senior leaders
- Author and review preclinical study reports to support regulatory submissions
- Apply an engineering mindset using a design-build-test-learn framework
- Coach and mentor junior scientists in a multidisciplinary team
This Role Requires:
- Experience evaluating DNA- or RNA-based therapeutics in small-animal models
- Hands-on molecular biology experience
- Experience mentoring/managing research associates
- Excellent communication and presentation skills
Preferred:
- Ph.D. in neuroscience, gene therapy, or related discipline
- 5+ years combined postdoctoral and industry experience in biotechnology, genetic medicines, or CNS drug discovery
- Knowledge of both viral and non-viral genetic medicine delivery modalities
Application:
- Apply now.
- Design experiments to evaluate efficacy, target engagement, and delivery efficiency of viral and non-viral therapeutic candidates across CNS disease models
- Design AAV transgene cassettes to optimize therapeutic efficacy
- Lead a team of associates in executing experiments and analyzing primary data
- Interpret complex datasets and integrate findings with scientific literature to propose data-driven next steps
- Communicate project strategy, scientific vision, and data updates to senior leaders
- Author and review preclinical study reports to support regulatory submissions
- Apply an engineering mindset using a design-build-test-learn framework
- Coach and mentor junior scientists in a multidisciplinary team
This Role Requires:
- Experience evaluating DNA- or RNA-based therapeutics in small-animal models
- Hands-on molecular biology experience
- Experience mentoring/managing research associates
- Excellent communication and presentation skills
Preferred:
- Ph.D. in neuroscience, gene therapy, or related discipline
- 5+ years combined postdoctoral and industry experience in biotechnology, genetic medicines, or CNS drug discovery
- Knowledge of both viral and non-viral genetic medicine delivery modalities
Application:
- Apply now.