Principal Scientist, Molecular Genomics

Role: Principal Scientist in Molecular Genomics responsible for developing, optimizing, and validating PCR and NGS-based biomarker assays supporting translational medicine and clinical programs. Objectives include generating high-quality genomic data to inform clinical trial decision-making and advance pipeline development. Responsibilities encompass assay strategy development, technology evaluation, assay design, qualification, validation, troubleshooting, and oversight of clinical sample analysis, collaborating with cross-functional teams like data analysis, biostats, and clinical operations. Qualifications: Bachelor's (8+ years), Master's (6+ years), or Ph.D. (4+ years) in Life Sciences with extensive hands-on experience in molecular assay development, particularly PCR, qPCR, NGS, gene expression profiling, and ctDNA technologies. Must demonstrate expertise in assay lifecycle management, validation, troubleshooting, and vendor oversight. Preferred skills include experience with clinical genomics assays in pharma/biotech, knowledge of assay quality control, and familiarity with bioinformatics interfaces. High-value biopharma specifics: focus on translational and clinical biomarker development, genomics platforms, and support for clinical trial phases. Collaboration with multiple scientific and operational teams is essential. Work setup is not specified, but the role involves laboratory-based activities with potential vendor interactions and cross-functional engagement.