Principal Scientist, Lab Platform Disruptive Technologies

Role: Lead development of innovative lab-based technologies for biologics discovery, focusing on rapid, high-throughput data generation to accelerate therapeutic programs. Responsibilities: develop and mature quantitative assays and scalable capabilities for biologics hit identification and optimization; craft a technology platform roadmap; collaborate with computational teams to integrate discovery workflows; drive improvements in data richness, speed, and reproducibility; lead and contribute hands-on to method development; establish benchmarks and success criteria. Requirements: PhD in Biochemistry, Bioengineering, Chemical Biology, or related field with 7+ years industry experience, or MS/BS with 12+ years; expertise in high-throughput quantitative methods such as pooled binding assays, cell-based endpoint assays, protein arrays, microfluidics; proven leadership and mentoring skills; strong biochemistry/biophysical characterization background. Preferred: understanding of protein structure-function, in vitro transcription/translation, biophysical protein characterization, and AI/ML workflows. High-Value: biologics discovery, biologics modalities, cell/gene therapies, leveraging GenAI/ML, Cambridge MA location, 10% travel. The role emphasizes cross-functional collaboration with protein engineering and data science teams, with a focus on advancing next-generation biologics discovery technologies.