Principal Scientist II, Imaging Expert- Clinical Imaging & Analytics

Role Summary

Principal Scientist II, Imaging Expert- Clinical Imaging & Analytics. The Imaging Expert will join the Clinical Imaging team to provide scientific, technical and operational support on the use of imaging in drug development, interacting with clinical trial teams to establish imaging endpoints across diverse therapeutic areas. This role offers exposure to biomarkers and readouts for efficacy and safety across translational development.

Responsibilities

• Act as an internal expert in PET and/or SPECT with focus on clinical trials
• Perform exploratory analysis on imaging data collected in clinical trials
• Drive development of novel imaging endpoints to address key scientific questions
• Identify and/or develop novel imaging techniques and endpoints, and implement them into clinical trials
• Partner with internal senior imaging experts to develop and execute ‚Äúfit for purpose‚Äù imaging strategy
• Collaborate and execute imaging readouts with internal operational support and external contract research organizations (CRO)
• Implement Imaging in clinical trials to add critical insights on patient eligibility, efficacy, safety, and mechanism of action
• Ensure quality and timely execution of imaging trials to deliver critical drug development decisions; be agile and responsive to clinical teams during the course of design, execution and interpretation of imaging trials
• Develop and manage network of external experts; synthesize inputs and customize for specific protocols
• Collaborate with Research teams to develop and lead translational imaging studies
• Drive molecular imaging and ligand development from late pre-clinical to clinical

Qualifications

• PhD or MD or MD/PhD with 3+ years of experience in PET and/or SPECT imaging in academia, industry or CRO
• Technical knowledge of PET and SPECT, including hands-on analysis as applied to clinical readouts
• Track record of innovative research across imaging modalities
• Experience in clinical Radioligand/Radiopharmaceutical Therapy (RLT/RPT) is a plus
• Experience in Regulatory submission, FIH, Dosimetry and receptor occupancy of molecular ligands is a plus
• Ability to balance external science with project needs
• Understanding of clinical trial design, endpoints statistics and clinical data flow is a plus
• Experience with clinical protocol writing is a plus
• Track record of project management and experience working with imaging CROs is a plus
• Proactive, self-motivated and independent working style; able to work in a multidisciplinary team
• Ability to drive for results with a sense of urgency and accountability
• Comfort working in a matrixed, supportive organization
• Proficiency in English with strong communication skills

Skills

• Imaging modalities: PET, SPECT
• Clinical trial collaboration and imaging readouts
• Translational imaging and biomarker integration
• Protocol development and project management
• Data analysis and interpretation of imaging endpoints

Education

• PhD/MD/MD-PhD in a relevant field; advanced training in molecular imaging or radiology preferred