Principal Scientist I, Biologics Analytical R&D (External Programs)
AbbVie
August 30, 2026
Remote friendly (North Chicago, IL)
United States
$124,500 - $236,500 USD yearly
Clinical Research and Development
Major Responsibilities:
- Develop and communicate analytical strategies for stability studies, product analytical control strategies, comparability studies, and extended characterization of biologics.
- Collaborate with third-party laboratories to meet CMC timelines.
- Interpret and identify data trends in key analytical release and stability assays.
- Author and/or review regulatory documents, lab data, technical memos, and reports.
- Advise peers and senior management; mentor others in project management and analytical strategy development.
- Demonstrate scientific excellence in analytical characterization (internally and externally) and foster consortia collaboration.
- Lead/participate in continuous improvement initiatives.
- Follow corporate standards for code of conduct, safety, and GxP compliance.
Qualifications:
- MS (12+ years) or PhD (6+ years) in Chemistry, Biochemistry, or Biology; 6+ years pharmaceutical laboratory experience.
- Preferred: experience leading project management for analytical development of biologic compounds (mAbs, ADCs, and/or fusion proteins).
- Strong knowledge of protein HPLC (SEC, IEX, HIC), capillary electrophoresis, and other protein separation techniques.
- Demonstrated scientific writing and excellent verbal communication.
- Preferred: experience with LIMS, CDS, ELN.
- Preferred: statistical knowledge (capability analysis, gauge R&R, DOE).
Benefits:
- Paid time off (vacation, holidays, sick), medical/dental/vision insurance, and 401(k) for eligible employees.
- Eligible to participate in long-term incentive programs.
- Develop and communicate analytical strategies for stability studies, product analytical control strategies, comparability studies, and extended characterization of biologics.
- Collaborate with third-party laboratories to meet CMC timelines.
- Interpret and identify data trends in key analytical release and stability assays.
- Author and/or review regulatory documents, lab data, technical memos, and reports.
- Advise peers and senior management; mentor others in project management and analytical strategy development.
- Demonstrate scientific excellence in analytical characterization (internally and externally) and foster consortia collaboration.
- Lead/participate in continuous improvement initiatives.
- Follow corporate standards for code of conduct, safety, and GxP compliance.
Qualifications:
- MS (12+ years) or PhD (6+ years) in Chemistry, Biochemistry, or Biology; 6+ years pharmaceutical laboratory experience.
- Preferred: experience leading project management for analytical development of biologic compounds (mAbs, ADCs, and/or fusion proteins).
- Strong knowledge of protein HPLC (SEC, IEX, HIC), capillary electrophoresis, and other protein separation techniques.
- Demonstrated scientific writing and excellent verbal communication.
- Preferred: experience with LIMS, CDS, ELN.
- Preferred: statistical knowledge (capability analysis, gauge R&R, DOE).
Benefits:
- Paid time off (vacation, holidays, sick), medical/dental/vision insurance, and 401(k) for eligible employees.
- Eligible to participate in long-term incentive programs.