Principal Scientist (Director), Translational Medicine - Cardiovascular

Role: Principal Scientist (Clinical Director) leading early clinical development of cardiovascular therapeutics, focusing on Phase 1 and 2 studies. Responsibilities: design and execute clinical strategies for novel compounds from Preclinical Candidate approval through Proof-of-Concept, develop biomarker strategies, validate clinical platforms, and support target identification/validation. Collaborate broadly across discovery, translational, and late-stage clinical teams; provide clinical pharmacology input for worldwide regulatory filings; communicate study results to governance teams. Requirements: MD or MD/PhD with proven clinical research record, biomedical research background, and strong communication skills; 10+ years in clinical medicine, translational research, or early drug development. Preferred: clinical subspecialty in cardiology, nephrology, or pulmonary; clinical board certification; translational research experience. High-Value: cardiovascular disease focus, early clinical development, biomarker integration, cross-functional collaboration, hybrid work model, ~10% travel.