Principal Scientist, Diagnostics
Gilead Sciences
August 20, 2026
Remote friendly (San Francisco Bay Area)
United States
Clinical Research and Development
Essential Duties and Job Functions
- Define diagnostic strategies for individual oncology programs, aligning biomarker objectives, clinical development plans, and broader portfolio diagnostic strategies in partnership with key cross-functional stakeholders.
- Develop and oversee integrated diagnostic project plans, coordinating internal teams and external partners to ensure resourcing, budgets, regulatory activities, CRO support, and operational execution to meet program objectives and timelines.
- Lead Diagnostic Sub Teams to execute diagnostic strategy from inception through regulatory approval, leveraging cross-functional expertise, third-party diagnostic partners, and central laboratories across global regions.
- Provide diagnostic subject matter expertise to multidisciplinary drug development teams.
Responsibilities
- Reporting to the Head of Oncology Diagnostics within the Diagnostics Group and participate as a member of relevant cross-functional drug development teams.
- Represent the diagnostic function on multiple global program teams to integrate diagnostic considerations into strategy and timelines.
- Lead Diagnostic Sub Teams and co-lead diagnostic partner teams to execute diagnostic strategy across multiple oncology programs.
- Develop, articulate, and manage integrated diagnostic project plans with biomarker, regulatory, clinical development, clinical operations, quality, and external partners.
- Work independently in a fast-paced matrix environment to align stakeholders, marshal resources, and integrate diagnostic development into broader drug development.
Skills / Qualifications
- Demonstrated ability to develop oncology diagnostic strategies aligning biomarker hypotheses, clinical objectives, assay requirements, and patient-selection needs.
- Knowledge of diagnostic platforms including IHC, NGS, flow cytometry, and digital pathology.
- Knowledge of clinical study design and diagnostic regulatory requirements; integrate diagnostic, clinical, regulatory, and commercial timelines across global development/lifecycle.
- Scientific leadership, communication, collaboration; detail-oriented with strong record keeping; independent, flexible self-starter.
- Proven publication record; understanding of IP and contracting terms desired.
Experience
- 10+ years with BA/BS, 8+ years with MA/MS, or 2+ years with MD or PhD; diagnostic strategy/assay development experience supporting oncology drug development preferred.
Application Instructions
- Apply via the Internal Career Opportunities portal in Workday.
- Define diagnostic strategies for individual oncology programs, aligning biomarker objectives, clinical development plans, and broader portfolio diagnostic strategies in partnership with key cross-functional stakeholders.
- Develop and oversee integrated diagnostic project plans, coordinating internal teams and external partners to ensure resourcing, budgets, regulatory activities, CRO support, and operational execution to meet program objectives and timelines.
- Lead Diagnostic Sub Teams to execute diagnostic strategy from inception through regulatory approval, leveraging cross-functional expertise, third-party diagnostic partners, and central laboratories across global regions.
- Provide diagnostic subject matter expertise to multidisciplinary drug development teams.
Responsibilities
- Reporting to the Head of Oncology Diagnostics within the Diagnostics Group and participate as a member of relevant cross-functional drug development teams.
- Represent the diagnostic function on multiple global program teams to integrate diagnostic considerations into strategy and timelines.
- Lead Diagnostic Sub Teams and co-lead diagnostic partner teams to execute diagnostic strategy across multiple oncology programs.
- Develop, articulate, and manage integrated diagnostic project plans with biomarker, regulatory, clinical development, clinical operations, quality, and external partners.
- Work independently in a fast-paced matrix environment to align stakeholders, marshal resources, and integrate diagnostic development into broader drug development.
Skills / Qualifications
- Demonstrated ability to develop oncology diagnostic strategies aligning biomarker hypotheses, clinical objectives, assay requirements, and patient-selection needs.
- Knowledge of diagnostic platforms including IHC, NGS, flow cytometry, and digital pathology.
- Knowledge of clinical study design and diagnostic regulatory requirements; integrate diagnostic, clinical, regulatory, and commercial timelines across global development/lifecycle.
- Scientific leadership, communication, collaboration; detail-oriented with strong record keeping; independent, flexible self-starter.
- Proven publication record; understanding of IP and contracting terms desired.
Experience
- 10+ years with BA/BS, 8+ years with MA/MS, or 2+ years with MD or PhD; diagnostic strategy/assay development experience supporting oncology drug development preferred.
Application Instructions
- Apply via the Internal Career Opportunities portal in Workday.