Principal Scientist, Compound Hub Lab Leader, Compound Management

Role Summary

Internal job title: Principal Scientist I (Level 4). Location: Cambridge, MA, onsite. We are seeking a highly motivated, detail-oriented and experienced compound logistics expert and lab leader to join our CM group in Cambridge. You and your lab team will accelerate drug discovery by producing high-quality compound stocks in various formats and implementing new capabilities in the Compound Hub (CPH), working closely with global DSc CM teams in Cambridge and Basel.

Responsibilities

• Leading and managing the Compound Hub team (CPH) in Cambridge (500 compound orders per workday)
• Working closely with a large community of compound requestors, recipients and CROs
• Coordinating CPH operations with compound management colleagues at other sites
• Validate new compound handling systems (dissolution, aliquoting, sorting…) and processes in close collaboration with the CM automation engineering teams
• Execute the Compound Hub process from weighing to distribution
• Develop, document and maintain SOPs for process and quality control
• Proactively identify and implement improvements to enhance system performance and reliability
• Track key performance indicators to assess the effect of enhancements and new automation on project timelines
• Present compound management activities and study results in cross-functional meetings
• Lead and develop a team of one associate and two contractors

Qualifications

• Required: BS or MS in Chemistry, Biochemistry, Engineering, or related field, with 10+ years’ relevant experience, or PhD with 5+ years relevant experience
• Required: Strong expertise in compound logistics processes and automation
• Required: Proven experience in compound management in a LMW drug discovery organization
• Required: High attention to detail and commitment to operational excellence
• Required: Strong organizational and time-management skills
• Required: Ability to work independently and collaboratively within multidisciplinary global teams
• Required: Flexibility and responsiveness to shifting priorities
• Required: Excellent written, verbal, and interpersonal communication skills