Principal Scientist, Clinical Research - Immunology/Dermatology
Merck
July 03, 2026
Remote friendly (Rahway, NJ)
United States
Clinical Research and Development
Clinical Director (Principal Scientist)
Responsibilities:
- Strategically plan and direct late-stage clinical research for investigational Immunology compounds across the full clinical development cycle (indication selection, study design, initiation, execution, monitoring, analysis, regulatory filings, and publication).
- Evaluate pre-clinical/translational work to create early clinical development plans and Investigational New Drug (IND) applications.
- Support business development assessments to grow the Immunology pipeline.
- Develop clinical development strategies and plan clinical trials (design, operational plans, study settings).
- Monitor and manage ongoing/new clinical trials.
- Analyze and summarize clinical findings to inform safety/efficacy decisions and support regulatory submissions, clinical study reports, and publications.
- Participate in internal and joint internal/external research project teams.
- Supervise Clinical Scientists; collaborate cross-functionally with commercialization, regulatory affairs, statistics, and manufacturing.
- Maintain scientific expertise (stay current on developments, identify strong investigators, build external collaboration in Rheumatology, attend scientific meetings).
- Author development documents/budgets/position papers; facilitate global collaborations; travel ~20% (also reflected elsewhere as ~10%).
Education:
- M.D., D.O., M.D./PhD, or D.O./PhD.
Required:
- 5+ years clinical and/or development experience (academia, clinical medicine, and/or corporate clinical development).
- Demonstrated scientific scholarship/achievement.
- Strong interpersonal and cross-functional collaboration skills.
Preferred:
- Phase 2 or 3 trial design/execution experience in rheumatologic diseases.
Required Skills:
- Allergy and Immunology, Clinical Development, Clinical Immunology/Research/Trials, Drug Investigation, Immunology, Statistics, Strategic Planning.
Application:
- Apply via https://jobs.merck.com/us/en (or Workday Jobs Hub). Apply by the deadline listed on the posting (job posting effective until 11:59:59PM the day before 07/27/2026).
Responsibilities:
- Strategically plan and direct late-stage clinical research for investigational Immunology compounds across the full clinical development cycle (indication selection, study design, initiation, execution, monitoring, analysis, regulatory filings, and publication).
- Evaluate pre-clinical/translational work to create early clinical development plans and Investigational New Drug (IND) applications.
- Support business development assessments to grow the Immunology pipeline.
- Develop clinical development strategies and plan clinical trials (design, operational plans, study settings).
- Monitor and manage ongoing/new clinical trials.
- Analyze and summarize clinical findings to inform safety/efficacy decisions and support regulatory submissions, clinical study reports, and publications.
- Participate in internal and joint internal/external research project teams.
- Supervise Clinical Scientists; collaborate cross-functionally with commercialization, regulatory affairs, statistics, and manufacturing.
- Maintain scientific expertise (stay current on developments, identify strong investigators, build external collaboration in Rheumatology, attend scientific meetings).
- Author development documents/budgets/position papers; facilitate global collaborations; travel ~20% (also reflected elsewhere as ~10%).
Education:
- M.D., D.O., M.D./PhD, or D.O./PhD.
Required:
- 5+ years clinical and/or development experience (academia, clinical medicine, and/or corporate clinical development).
- Demonstrated scientific scholarship/achievement.
- Strong interpersonal and cross-functional collaboration skills.
Preferred:
- Phase 2 or 3 trial design/execution experience in rheumatologic diseases.
Required Skills:
- Allergy and Immunology, Clinical Development, Clinical Immunology/Research/Trials, Drug Investigation, Immunology, Statistics, Strategic Planning.
Application:
- Apply via https://jobs.merck.com/us/en (or Workday Jobs Hub). Apply by the deadline listed on the posting (job posting effective until 11:59:59PM the day before 07/27/2026).