Principal Scientist, Clinical Research - Immunology/Dermatology
Merck
July 03, 2026
Remote friendly (North Wales, PA)
United States
Clinical Research and Development
Clinical Director (Principal Scientist) — Strategic planning and direction of clinical research for investigational compounds in Immunology (late-stage development). Manage the full cycle of clinical development: select disease indications, design studies, initiate, execute, monitor, analyze, support regulatory filings, and publication.
Responsibilities:
- Evaluate pre-clinical/translational work to develop early clinical plans and INDs.
- Support business development assessments of external opportunities to grow the Immunology pipeline.
- Develop clinical development strategies and plan clinical trials (design, operational plans, settings).
- Monitor and manage conduct of ongoing or new clinical trials.
- Analyze/summarize clinical findings to support safety/efficacy decisions and submissions (clinical study reports/publications).
- Participate in internal and joint internal/external research project teams.
- Supervise Clinical Scientists executing clinical studies.
- Partner cross-functionally with commercialization, regulatory affairs, statistics, and manufacturing.
- Maintain scientific knowledge by tracking developments, identifying strong investigators, building rheumatology expert collaborations, and attending scientific meetings.
- Author development documents, presentations, budgets, and position papers; facilitate global collaborations; travel ~20% to manage clinical research.
Education/Experience:
- M.D., D.O., M.D./PhD, or D.O./PhD.
- 5+ years clinical and/or development experience (academia, clinical medicine, and/or corporate clinical development).
- Record of scientific scholarship/achievement.
- Preferred: phase 2 or 3 trial design/execution in rheumatologic diseases.
Required Skills:
- Allergy & Immunology, Clinical Development, Clinical Immunology, Clinical Research, Clinical Trials, Dermatology, Drug Investigation, Immunology, Statistics, Strategic Planning.
Application:
- Apply via jobs.merck.com/us/en (or Workday Jobs Hub if current employee). Application deadline listed on posting.
Responsibilities:
- Evaluate pre-clinical/translational work to develop early clinical plans and INDs.
- Support business development assessments of external opportunities to grow the Immunology pipeline.
- Develop clinical development strategies and plan clinical trials (design, operational plans, settings).
- Monitor and manage conduct of ongoing or new clinical trials.
- Analyze/summarize clinical findings to support safety/efficacy decisions and submissions (clinical study reports/publications).
- Participate in internal and joint internal/external research project teams.
- Supervise Clinical Scientists executing clinical studies.
- Partner cross-functionally with commercialization, regulatory affairs, statistics, and manufacturing.
- Maintain scientific knowledge by tracking developments, identifying strong investigators, building rheumatology expert collaborations, and attending scientific meetings.
- Author development documents, presentations, budgets, and position papers; facilitate global collaborations; travel ~20% to manage clinical research.
Education/Experience:
- M.D., D.O., M.D./PhD, or D.O./PhD.
- 5+ years clinical and/or development experience (academia, clinical medicine, and/or corporate clinical development).
- Record of scientific scholarship/achievement.
- Preferred: phase 2 or 3 trial design/execution in rheumatologic diseases.
Required Skills:
- Allergy & Immunology, Clinical Development, Clinical Immunology, Clinical Research, Clinical Trials, Dermatology, Drug Investigation, Immunology, Statistics, Strategic Planning.
Application:
- Apply via jobs.merck.com/us/en (or Workday Jobs Hub if current employee). Application deadline listed on posting.