Principal Scientist, Clinical Pharmacology & Pharmacometrics

Role: Principal Scientist in Clinical Pharmacology & Pharmacometrics within Johnson & Johnson's Innovative Medicine division, focusing on developing and executing clinical pharmacology strategies for drug candidates. Responsibilities include designing PK/PD studies, applying model-informed drug development (MIDD) principles, analyzing dose-response relationships, and supporting regulatory submissions. The role involves leading cross-functional teams, managing pharmacometric analyses, and representing pharmacology in regulatory meetings. Qualifications: PhD in Pharmaceutical Sciences, Clinical Pharmacology, or related field; 5+ years' experience in pharma R&D; expertise in PK, PD, MIDD, and modeling tools (e.g., NONMEM, R, Gastroplus). High-value biopharma specifics include emphasis on quantitative methods, translational medicine, and interaction with regulatory agencies. The position supports established brands and post-approval development, with some international travel (~5%). Work setup: locations in NJ or PA, with potential for hybrid arrangements.