Position Summary
- Translational scientist to identify/discover cardiovascular biomarkers to advance late-discovery programs into early clinical trials. Collaborate with development; may serve as discovery-to-development liaison.
Responsibilities
- Define pharmacodynamic biomarkers of response and disease progression; explain clinical translation.
- Design and execute experiments; interpret results.
- Modify in-life experiments as needed.
- Lead studies to completion (internal analysis or manage CROs externally).
- Critically evaluate programs; present findings/recommendations to discovery teams and leadership.
- Document/critically review and present data in a timely manner.
- Provide actionable study results to cross-functional teams.
- Provide hands-on training/guidance to team members.
- Author reports, abstracts, and publications.
Basic Qualifications
- Bachelorβs degree + 8+ years (academic/industry)
OR Masterβs + 6+ years
OR Ph.D. (Life Sciences) + 4+ years.
Preferred Qualifications / Skills
- Ph.D. in relevant field (Physiology/Pharmacology/Biology/Biochemistry or related) with industry experience and post-terminal training; or PharmD/DVM/MD with strong basic-science/drug-discovery record; or M.S. with 5+ years relevant industry experience.
- Strong cardiovascular physiology and preclinical/clinical methodologies; imaging biomarkers (ultrasound-echo, MRI, PET).
- Apply 3Rs; focus on species-specific animal research considerations.
- Rodent handling experience.
- iPSC-CM, primary cardiac cells, and/or engineered heart tissue culture; biochemical/functional measurements.
- Excellent, reproducible lab skills; manage collaborators/timelines.
Compensation & Benefits (explicit)
- Princeton, NJ: $135,800β$164,563.
- Health, wellbeing support, 401(k), disability/life/insurance; paid time off (flexible/specified vacation and holidays by location).