Principal Scientist, Cardiovascular Translational Biomarker
Bristol Myers Squibb
6 months ago
On-site
Princeton, NJ
Clinical Research and Development
Position Summary: Translational scientist (cardiovascular biology) to identify and discover biomarkers supporting progression of late-discovery programs into early-phase clinical trials and beyond; partner closely with development.
Responsibilities:
- Define pharmacodynamic biomarkers of response and disease progression; explain translation to clinic.
- Use strong experimental design and technical skills (cell culture of relevant cell lines/primary cells; immunoassays such as ELISA/MSD; IHC; protein signaling; qPCR) and interpret results.
- Modify experiments in-life as needed.
- Lead studies to completion via internal sample analysis or by directing CROs.
- Critically evaluate programs; present findings/recommendations to teams and leadership.
- Document and communicate experimental data timely; collaborate cross-functionally.
- Provide hands-on training; author reports/abstracts/publications.
Basic Qualifications:
- Bachelor’s (8+ years) OR Master’s (6+ years) OR Ph.D./equivalent (4+ years) in Life Sciences.
Preferred Qualifications/Skills:
- Ph.D. in Physiology/Pharmacology/Biology/Biochemistry (or related) with industry experience; imaging biomarkers knowledge (ultrasound-echo, MRI, PET).
- Apply animal research 3Rs; hands-on rodent handling.
- Expertise culturing/measuring in iPSC-CM, primary cardiac cells, and/or engineered heart tissues.
- Excellent, reproducible lab skills; manage collaborators; self-motivated, detail-oriented, collaborative in matrix teams.
Benefits (explicitly stated):
- Health coverage (medical/pharmacy/dental/vision), wellbeing programs (incl. EAP), 401(k) and insurance/disability benefits.
- Paid time off (flexible time off/unlimited or 160 hours vacation depending on role/location, plus holidays).
Responsibilities:
- Define pharmacodynamic biomarkers of response and disease progression; explain translation to clinic.
- Use strong experimental design and technical skills (cell culture of relevant cell lines/primary cells; immunoassays such as ELISA/MSD; IHC; protein signaling; qPCR) and interpret results.
- Modify experiments in-life as needed.
- Lead studies to completion via internal sample analysis or by directing CROs.
- Critically evaluate programs; present findings/recommendations to teams and leadership.
- Document and communicate experimental data timely; collaborate cross-functionally.
- Provide hands-on training; author reports/abstracts/publications.
Basic Qualifications:
- Bachelor’s (8+ years) OR Master’s (6+ years) OR Ph.D./equivalent (4+ years) in Life Sciences.
Preferred Qualifications/Skills:
- Ph.D. in Physiology/Pharmacology/Biology/Biochemistry (or related) with industry experience; imaging biomarkers knowledge (ultrasound-echo, MRI, PET).
- Apply animal research 3Rs; hands-on rodent handling.
- Expertise culturing/measuring in iPSC-CM, primary cardiac cells, and/or engineered heart tissues.
- Excellent, reproducible lab skills; manage collaborators; self-motivated, detail-oriented, collaborative in matrix teams.
Benefits (explicitly stated):
- Health coverage (medical/pharmacy/dental/vision), wellbeing programs (incl. EAP), 401(k) and insurance/disability benefits.
- Paid time off (flexible time off/unlimited or 160 hours vacation depending on role/location, plus holidays).