Principal Scientist, Biomarker & Drug Intelligence

Role Summary

The Principal Curation Scientist, Biomarker & Drug Intelligence will serve as a pivotal member of the biomarker and drug intelligence team supporting the Caris Molecular Intelligence (CMI) knowledge base. This role involves working closely with the Vice President of the Biomarker & Drug Intelligence team and collaboratively across internal and cross-functional departments to update and maintain Caris precision-oncology products and services, including the Oncology Precision Medicine report which guides biomarker-driven treatment options for clinical use.

Responsibilities

• Lead strategic programs that continuously scan scientific, clinical-trial, and regulatory pipelines to surface high-impact biomarkers and drug candidates for precision-oncology products and services.
• Architect and govern enterprise-wide knowledge-management frameworks, setting best-practice standards for cataloging, harmonizing, and integrating multi-omic literature so downstream reporting and analytics remain current.
• Serve as a scientific spokesperson for designing and delivering high impact presentations and briefings that shape internal product strategy.
• Support the quality-management system for medical reporting, authoring and approving SOPs, monitoring key quality indicators, and partnering with Regulatory Affairs to ensure compliance.
• Support the vision and methodology for user-acceptance testing (UAT), by defining test architectures, success criteria, and automation roadmaps that guarantee scalable, fault-tolerant clinical-report updates.
• Direct cross-functional validation initiatives, unifying data scientists, software engineers, pathologists, and medical directors to stress-test releases and ensure every deliverable meets clinical, operational, and user-experience benchmarks.
• Champion organizational learning and external engagement, by mentoring scientists across disciplines, spearheading tumor-board and training curricula, and representing the company in consortia, standards bodies, and key scientific forums.

Qualifications

• Required: Ph.D., M.D./Ph.D., or Pharm.D. in a Biological Science related to Cancer Biology or Pharmaceutical Sciences.
• Required: Minimum of seven years of industry experience in Biopharma, Biotechnology, or a related sector.
• Required: The position requires the individual to live within the Phoenix, Arizona metropolitan area.
• Required: Proven experience in curating literature using public databases, tools, and resources.
• Required: Proficiency with Microsoft Office Suite (Excel, Word, PowerPoint), reference management tools (Endnote), virtual meeting platforms and information mapping/visualization software (e.g., MindManager).

Preferred Qualifications

• More than ten years of experience in the biotechnology and/or pharmaceutical industries.
• Strong foundation in Cancer Biology, Molecular and Cellular Biology, Genetics, or a related field relevant to precision medicine in oncology.
• Familiarity with precision medicine concepts and analytical platforms used to generate proteomic and genomic data for guiding patient therapy.
• Exceptional communication and presentation skills, with the ability to synthesize complex scientific information into clear, actionable insights for diverse audiences.
• Demonstrated ability to effectively communicate, coordinate, and build strong relationships across diverse teams and departments to achieve shared goals and alignment throughout projects.
• Able to analyze complex information, weigh alternatives, and make timely decisions under pressure while considering both short-term impacts and long-term goals.
• Dedication to achieving high standards of excellence, contributing to the mission of improving patient outcomes in oncology.
• Experience interpreting clinical data in a clear, accurate, and tailored manner to address the needs of diverse stakeholders including healthcare professionals, cross-functional teams, executive leadership and regulatory bodies.

Education

• Ph.D., M.D./Ph.D., or Pharm.D. (as listed above)

Additional Requirements

• Periodic travel may be required.
• This position requires periodic travel and some evenings, weekends and/or holidays.
• Job may require after-hours response to emergency issues.
• Periodically scheduled on-call may require after-hours response for technical emergencies not explicitly related to assigned job responsibilities.
• At times may be required to work weekends/holidays.