Principal Scientist, Bioanalytical Research
Eli Lilly and Company
2 months ago
On-site
Indianapolis, IN
Clinical Research and Development
Primary Responsibilities:
- Develop and apply QQQ and high-resolution LC/MS approaches to characterize PK, biotransformation, and biodistribution of therapeutic proteins and new drug modalities in pre-clinical animal models.
- Serve as the bioanalytical representative with project teams to achieve project milestones.
- Prioritize workload and mentor staff scientists within a broad field bioanalytical team.
Job Requirements:
- M.S. in biochemistry/molecular biology, bioengineering, biology, pharmacology, chemistry, or equivalent field and 6+ years of work experience (or B.S. with 9+ years).
- Experience developing and implementing orbitrap mass spectrometry applications to investigate ADME properties of therapeutic proteins and new modalities (Large Molecules).
- Experience with wet biochemistry and sample preparation techniques for isolating biotherapeutics from biological matrices.
- Authorization to work in the United States full-time; Lilly will not provide support/sponsorship for work authorization/visas (including listed visa types).
Preferred Qualifications:
- Expertise in bioanalysis of siRNA or Antibody-Oligonucleotide Conjugates (AOC); assessing PK, efficacy, and toxicology profiles in preclinical models and presenting data.
- Knowledge of ADME principles of biotherapeutic drugs; proteomics methods and workflows (DDA, nano-LC, DIA, etc.), plus automation/higher throughput and biotransformation software tools.
- Excellent written and verbal communication; strong work planning, record keeping, and data analysis skills.
Benefits (as stated):
- Anticipated wage: $65,250 - $193,600; full-time employees may be eligible for a company bonus; comprehensive benefit program (e.g., 401(k), pension, vacation, medical/dental/vision, life insurance, time off/leave, well-being benefits).
- Develop and apply QQQ and high-resolution LC/MS approaches to characterize PK, biotransformation, and biodistribution of therapeutic proteins and new drug modalities in pre-clinical animal models.
- Serve as the bioanalytical representative with project teams to achieve project milestones.
- Prioritize workload and mentor staff scientists within a broad field bioanalytical team.
Job Requirements:
- M.S. in biochemistry/molecular biology, bioengineering, biology, pharmacology, chemistry, or equivalent field and 6+ years of work experience (or B.S. with 9+ years).
- Experience developing and implementing orbitrap mass spectrometry applications to investigate ADME properties of therapeutic proteins and new modalities (Large Molecules).
- Experience with wet biochemistry and sample preparation techniques for isolating biotherapeutics from biological matrices.
- Authorization to work in the United States full-time; Lilly will not provide support/sponsorship for work authorization/visas (including listed visa types).
Preferred Qualifications:
- Expertise in bioanalysis of siRNA or Antibody-Oligonucleotide Conjugates (AOC); assessing PK, efficacy, and toxicology profiles in preclinical models and presenting data.
- Knowledge of ADME principles of biotherapeutic drugs; proteomics methods and workflows (DDA, nano-LC, DIA, etc.), plus automation/higher throughput and biotransformation software tools.
- Excellent written and verbal communication; strong work planning, record keeping, and data analysis skills.
Benefits (as stated):
- Anticipated wage: $65,250 - $193,600; full-time employees may be eligible for a company bonus; comprehensive benefit program (e.g., 401(k), pension, vacation, medical/dental/vision, life insurance, time off/leave, well-being benefits).