Principal Scientist - ADME - Site Based, Princeton, NJ
Evotec
4 days ago
On-site
Princeton, NJ
Clinical Research and Development
What You'll Do
- Manage client and R&D projects to a high standard and within scheduled timeframes.
- Serve as a visible leader; support training and development to improve team knowledge and processes.
- Work with the VP to create and cascade short- and medium-term team vision and strategy.
- Serve as senior point of contact for operational and scientific support across ADME assays (troubleshooting, data analysis, interpretation).
- Lead cross-functional collaboration.
- Design and perform novel ADME assays.
- Conduct in vitro ADME assays manually and/or using automated liquid handling; manage multiple projects to meet timelines.
- Perform bioanalytical method development and quantification using UPLC-MS/MS.
- Analyze/interpret data to resolve issues and design next steps.
- Provide expert scientific support for ADME and drug metabolism studies across the company.
- Stay current with scientific literature and regulatory guidelines; inform the team of relevant developments.
- Provide practical scientific guidance and regularly present findings.
- Promote cross-functional collaboration; support staff contributions to collaborations.
- Coach, mentor, and line manage staff; assist with development plans and execution.
- Assist VP with succession planning.
- Manage and coordinate multiple projects/activities with a results-driven approach; improve assay processes and efficiency; encourage continuous improvement.
- Participate in internal and external partner meetings as needed.
- Ensure Health and Safety procedures are followed; complete mandatory training; maintain an up-to-date training record; participate in Evotalks and agree on targets.
Who You Are / Qualifications
- PhD (5+ years experience) in biology, chemistry, pharmaceutical sciences, or equivalent.
- Excellent writing and verbal communication.
- Strong organization and attention to detail.
- Detailed knowledge of bioanalysis within ADME/DMPK.
- Hands-on experience in bioanalytical method development and quantification of small molecules and peptides in complex matrices.
- Strong understanding of UPLC-MS/MS systems.
- Troubleshooting skills in assays and instrumentation.
- Understanding of pharmacokinetic parameter determination and interpretation.
- Experience applying information from scientific literature.
Compensation/Benefits
- Base pay range: $113,900–$154,100 (salaried exempt). Discretionary annual bonus; Medical, Dental, Vision; short- and long-term disability; company paid basic life insurance; 401(k) match; flexible work; generous paid time off and paid holidays; wellness and transportation benefits.
- Manage client and R&D projects to a high standard and within scheduled timeframes.
- Serve as a visible leader; support training and development to improve team knowledge and processes.
- Work with the VP to create and cascade short- and medium-term team vision and strategy.
- Serve as senior point of contact for operational and scientific support across ADME assays (troubleshooting, data analysis, interpretation).
- Lead cross-functional collaboration.
- Design and perform novel ADME assays.
- Conduct in vitro ADME assays manually and/or using automated liquid handling; manage multiple projects to meet timelines.
- Perform bioanalytical method development and quantification using UPLC-MS/MS.
- Analyze/interpret data to resolve issues and design next steps.
- Provide expert scientific support for ADME and drug metabolism studies across the company.
- Stay current with scientific literature and regulatory guidelines; inform the team of relevant developments.
- Provide practical scientific guidance and regularly present findings.
- Promote cross-functional collaboration; support staff contributions to collaborations.
- Coach, mentor, and line manage staff; assist with development plans and execution.
- Assist VP with succession planning.
- Manage and coordinate multiple projects/activities with a results-driven approach; improve assay processes and efficiency; encourage continuous improvement.
- Participate in internal and external partner meetings as needed.
- Ensure Health and Safety procedures are followed; complete mandatory training; maintain an up-to-date training record; participate in Evotalks and agree on targets.
Who You Are / Qualifications
- PhD (5+ years experience) in biology, chemistry, pharmaceutical sciences, or equivalent.
- Excellent writing and verbal communication.
- Strong organization and attention to detail.
- Detailed knowledge of bioanalysis within ADME/DMPK.
- Hands-on experience in bioanalytical method development and quantification of small molecules and peptides in complex matrices.
- Strong understanding of UPLC-MS/MS systems.
- Troubleshooting skills in assays and instrumentation.
- Understanding of pharmacokinetic parameter determination and interpretation.
- Experience applying information from scientific literature.
Compensation/Benefits
- Base pay range: $113,900–$154,100 (salaried exempt). Discretionary annual bonus; Medical, Dental, Vision; short- and long-term disability; company paid basic life insurance; 401(k) match; flexible work; generous paid time off and paid holidays; wellness and transportation benefits.