Principal Research Scientist, QTAS & ADME Sciences
AbbVie
June 30, 2026
On-site
North Chicago, IL
$124,500 - $236,500 USD yearly
Clinical Research and Development
Core Responsibilities:
- Evaluate novel in vitro tools/methods to improve prediction of human PK and drug-drug interaction (DDI) potential.
- Lead, mentor, and coach junior staff in in vitro drug metabolism practices.
- Liaise with QTAS and discovery biology/pharmacology/chemistry to build translational, mechanistic models.
- Communicate internally/externally on in vitro drug metabolism.
- Stay current on emerging literature and modeling/in vitro approaches.
- Publish results and present research (oral presentations; full-length publications).
Qualifications:
- BS (14+ years), MS (12+ years), or PhD (6+ years) in relevant scientific discipline.
- Experience with in vitro ADME experiments and DMPK projects (academic or industry).
- Deep knowledge of drug metabolism/ADME: enzyme kinetics, IVIVE, and DDI risk assessment.
- Strong publication record and strategic scientific leadership in in vitro ADME.
- Excellent communication/presentation; capable team player and independent contributor.
- Desired: experience in adjacent areas (drug permeability/transport, receptor pharmacology, pharmacokinetic modeling).
Benefits (as stated): paid time off (vacation/holidays/sick), medical/dental/vision insurance, 401(k), and eligibility for long-term incentive programs.
- Evaluate novel in vitro tools/methods to improve prediction of human PK and drug-drug interaction (DDI) potential.
- Lead, mentor, and coach junior staff in in vitro drug metabolism practices.
- Liaise with QTAS and discovery biology/pharmacology/chemistry to build translational, mechanistic models.
- Communicate internally/externally on in vitro drug metabolism.
- Stay current on emerging literature and modeling/in vitro approaches.
- Publish results and present research (oral presentations; full-length publications).
Qualifications:
- BS (14+ years), MS (12+ years), or PhD (6+ years) in relevant scientific discipline.
- Experience with in vitro ADME experiments and DMPK projects (academic or industry).
- Deep knowledge of drug metabolism/ADME: enzyme kinetics, IVIVE, and DDI risk assessment.
- Strong publication record and strategic scientific leadership in in vitro ADME.
- Excellent communication/presentation; capable team player and independent contributor.
- Desired: experience in adjacent areas (drug permeability/transport, receptor pharmacology, pharmacokinetic modeling).
Benefits (as stated): paid time off (vacation/holidays/sick), medical/dental/vision insurance, 401(k), and eligibility for long-term incentive programs.