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Principal Research Scientist II, Process Chemistry

AbbVie
August 21, 2026
Full-time
Remote friendly (North Chicago, IL)
Worldwide
$268,500 - $268,500 USD yearly
Operations
Role: Principal Research Scientist II in Process Chemistry, focusing on the development and characterization of drug substance processes for AbbVie's clinical candidates, primarily small molecules. Responsibilities: lead and contribute to project teams for process development, optimize scalable synthetic routes, author regulatory documents, mentor staff, and collaborate across disciplines including organic and analytical chemistry, engineering, and drug development. Develop control strategies for cGMP manufacturing and drive continuous improvement initiatives. Requirements: BS (16+ years), MS (14+ years), or PhD (8+ years) in Chemistry or related field with extensive pharmaceutical laboratory experience; proven leadership in process development and GMP manufacturing; strong organic chemistry and mechanistic expertise; excellent collaboration and communication skills. Preferred: experience managing scientific teams and developing robust processes for drug substance manufacturing. HighValue: focus on small molecule process development, regulatory documentation, GMP manufacturing, cross-disciplinary teamwork within biotech/pharmaceutical environments. WorkSetup: not specified, but implies an operational laboratory setting.