Principal Research Scientist II, Computational Sciences, MPDD

Role: Principal Scientist II in computational chemistry within AbbVie's Molecular Profiling and Drug Delivery (MPDD) organization, focusing on advancing drug discovery through molecular design, profiling, and materials development across synthetic modalities. Responsibilities: lead the development, implementation, and optimization of physics-based and AI/ML computational models supporting medicinal chemistry, chemical transitions, and materials design; collaborate with cross-functional teams to integrate computational tools into drug discovery workflows; evaluate model performance, communicate findings, and guide project teams on model applicability; mentor scientists, build external partnerships, and stay abreast of scientific advances. Requirements: PhD in chemistry, pharmaceutical sciences, chemical engineering, computer science, or related field; 8+ years (or equivalent experience with master's or bachelor's degrees); extensive expertise in computational chemistry methods such as quantum mechanics, molecular dynamics, AI/ML; proven record of applying computational models across drug discovery stages; experience leading complex projects, mentoring, and external collaborations. High-Value: focus on small molecules across preclinical to clinical development, leveraging advanced computational techniques (quantum mechanics, AI/ML); leadership in model development and validation; cross-disciplinary collaboration with chemists, data scientists, materials scientists, and engineers; strong publication record preferred. Work setup: not specified.