Principal Research Scientist I or II, Solid State Chemistry
AbbVie
4 months ago
Remote friendly (North Chicago, IL)
United States
Other
Responsibilities:
- Lead identification and development of solid forms of synthetic drug substances for robust manufacturing processes and products, supporting assets through all phases of development.
- Develop and implement state-of-the-art computational tools to map and de-risk solid form landscape.
- Establish and utilize solid state and materials science characterization techniques (with automation and modeling) to define structure–property–performance relationships.
- Collaboratively develop manufacturing processes in the laboratory and demonstrate in the pilot plant to enable clinical supplies.
- Set project strategies, define responsibilities and timelines, provide leadership in a matrixed team setting, and establish/communicate/execute research plans.
- Supervise and mentor junior scientists and interns.
- Publish research findings and represent the organization at scientific conferences.
Qualifications:
- Principle Research Scientist I: Bachelor’s (14+ years industry); Master’s (12+ years); PhD (6+ years).
- Principle Research Scientist II: Bachelor’s (16+ years industry); Master’s (14+ years); PhD (8+ years).
- Preferred education: Biopharmaceutical Sciences, Physical Chemistry, Chemical Biology, Material Sciences, Chemical Engineering, or Biomedical Engineering.
- Strong knowledge of solid form development, design and control of associated unit operations, and analytical tools.
- Strong biopharmaceutical knowledge (e.g., salts/cocrystals), polymorphism, solid form/material properties assessment; experience with PXRD, thermal techniques, microscopy, particle size analysis, HPLC, etc.
- Highly desirable: CMC development of oral peptide; desirable: solid-form screening, physical properties characterization, and crystallization development of oral peptide, nucleic acid, and therapeutic protein.
- Proven ability to represent the department in cross-functional teams and expertise centers; develop/implement strategies aligned with functional goals.
- Creative, out-of-the-box problem solving; ability to identify emerging scientific trends and integrate into strategic plans.
- Record of independently leading research to meet short- and long-term goals; leveraging external innovations/resources.
- Excellent communication and partnership-building across organizational boundaries.
Benefits:
- Paid time off (vacation, holidays, sick); medical/dental/vision insurance; 401(k) (eligible employees).
- Eligible to participate in short-term incentive programs.
- Lead identification and development of solid forms of synthetic drug substances for robust manufacturing processes and products, supporting assets through all phases of development.
- Develop and implement state-of-the-art computational tools to map and de-risk solid form landscape.
- Establish and utilize solid state and materials science characterization techniques (with automation and modeling) to define structure–property–performance relationships.
- Collaboratively develop manufacturing processes in the laboratory and demonstrate in the pilot plant to enable clinical supplies.
- Set project strategies, define responsibilities and timelines, provide leadership in a matrixed team setting, and establish/communicate/execute research plans.
- Supervise and mentor junior scientists and interns.
- Publish research findings and represent the organization at scientific conferences.
Qualifications:
- Principle Research Scientist I: Bachelor’s (14+ years industry); Master’s (12+ years); PhD (6+ years).
- Principle Research Scientist II: Bachelor’s (16+ years industry); Master’s (14+ years); PhD (8+ years).
- Preferred education: Biopharmaceutical Sciences, Physical Chemistry, Chemical Biology, Material Sciences, Chemical Engineering, or Biomedical Engineering.
- Strong knowledge of solid form development, design and control of associated unit operations, and analytical tools.
- Strong biopharmaceutical knowledge (e.g., salts/cocrystals), polymorphism, solid form/material properties assessment; experience with PXRD, thermal techniques, microscopy, particle size analysis, HPLC, etc.
- Highly desirable: CMC development of oral peptide; desirable: solid-form screening, physical properties characterization, and crystallization development of oral peptide, nucleic acid, and therapeutic protein.
- Proven ability to represent the department in cross-functional teams and expertise centers; develop/implement strategies aligned with functional goals.
- Creative, out-of-the-box problem solving; ability to identify emerging scientific trends and integrate into strategic plans.
- Record of independently leading research to meet short- and long-term goals; leveraging external innovations/resources.
- Excellent communication and partnership-building across organizational boundaries.
Benefits:
- Paid time off (vacation, holidays, sick); medical/dental/vision insurance; 401(k) (eligible employees).
- Eligible to participate in short-term incentive programs.