Principal Research Scientist I, Multispecifics Engineering
AbbVie
September 30, 2026
Full-time
Remote friendly (Worcester, MA)
Worldwide
$236,500 - $236,500 USD yearly
Other
Role: Senior scientist supporting discovery biotherapeutics in multispecific biologics engineering, focusing on design, production, and characterization across multiple therapeutic areas. Responsibilities: lead molecule engineering efforts, serve as subject matter expert in multispecifics, manage 1β2 projects including timelines and decision-making, troubleshoot technical challenges, ensure report quality, and communicate findings internally and externally. Requirements: PhD or MS in Biochemistry, Biochemical Engineering, or related field; 6+ (PhD) or 12+ (MS) years in multispecific or antibody engineering; experience with protein design, expression, purification, and analytical technologies; strong knowledge of multispecific modalities and therapeutic landscapes such as immunology, oncology, and neuroscience. Preferred: CRO coordination, high-throughput screening, advanced protein analytics, pipeline management, and relevant patents/publications. High-Value: biologics, multispecifics (bispecifics/trispecifics), biologic discovery stage, leadership experience, cross-functional collaboration, and proficiency in related biopharma tech platforms. Work setup and travel details are not specified.